ArticlePloS one2020
The epidemiological risk factors of hand, foot, mouth disease among children in Singapore: A retrospective case-control study.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- Global epidemiological and aetiological patterns of hand, foot, and mouth disease: a country-level scoping synthesis.Journal of global health · 2026Article
- Epidemiological characteristics and spatiotemporal analysis of hand-foot-mouth disease in Shandong Province, China.International health · 2026Article
- Epidemiological characteristics and influential factors of hand, foot, and mouth disease reinfection in Southwest China, 2009-2022.BMC infectious diseases · 2025Article
- Influencing factors of hand, foot, and mouth disease based on structural equation modeling in Hubei, China.Scientific reports · 2025Article
- A serosurvey study of hand, foot and mouth disease in healthy children aged 6 to 71 months old in West Bandung and Bandung Region, Indonesia.BMC infectious diseases · 2025Observational
- Knowledge, attitudes, and practices status among caregivers of infants and toddlers towards hand, foot and mouth disease: a cross-sectional study.BMC public health · 2024Article
- A hybrid model for hand-foot-mouth disease prediction based on ARIMA-EEMD-LSTM.BMC infectious diseases · 2023Article
- Assessing the impact of COVID-19 interventions on the hand, foot and mouth disease in Guangdong Province, China: a Bayesian modeling study.Frontiers in public health · 2023Article
- Article
- Impact of the coronavirus disease 2019 interventions on the incidence of hand, foot, and mouth disease in mainland China.The Lancet regional health. Western Pacific · 2022Article
- The knowledge, attitudes and practices of hand, foot, and mouth disease prevention strategies amongst parents and educators of children under 5 years amidst COVID-19 pandemic: A cross-sectional study.Frontiers in public health · 2022Article
- Global emergence of Enterovirus 71: a systematic review.Beni-Suef University journal of basic and applied sciences · 2022Review
- Molecular Epidemiological Study of Hand, Foot, and Mouth Disease in a Kindergarten-Based Setting in Bangkok, Thailand.Pathogens (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The incidence of hand, foot, and mouth disease (HFMD) is increasing over the years despite current prevention and control policies in Singapore. A retrospective case-control study was conducted among parents whose children attended childcare centres in Singapore to assess the epidemiological risk factors associated with HFMD among children below 7 years old. Parents of 363 children with HFMD (as cases) and 362 children without HFMD (as controls) were enrolled from 22 childcare centres. Data of potential risk factors were collected through a standardised self-administered questionnaire from parents which include demographics and hygiene practices. Multivariate analysis were adjusted for age group, parent's education level, mother's age, HFMD-infected siblings, and preschool admission period. Child's age between 1.5 and 4.9 years, child who had been in childcare for more than 1.9years, having HFMD-infected siblings, two or more children in a family, higher educated parents, parents who had HFMD episode previously, wash toys with soap once every two to three weeks, sanitise toys once every two to three weeks, out-sourced cleaner in childcare centre, no domestic helper at home and more than 22 children in a classroom were independent risk factors of HFMD. These evidence provide crucial implications to guide more effective prevention and control of HFMD in Singapore.
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