Evidence map›Paper›PMID 32780619›Full record

ArticleThe Journal of international medical research2020

Effects of statins on clinical outcomes in hospitalized patients with community-acquired pneumonia.

Rony M Zeenny, Hanine Mansour, Wissam K Kabbara, Nibal Chamoun, Myriam Audi, Yasmina Yared, Pascale Salameh

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Rony M ZeennyAmerican University of Beirut Medical Center, Beirut, Lebanon.
Hanine MansourLebanese American University, School of Pharmacy, Byblos, Lebanon.ORCID https://orcid.org/0000-0001-6383-0288
Wissam K KabbaraLebanese American University, School of Pharmacy, Byblos, Lebanon.ORCID https://orcid.org/0000-0002-7310-9192
Nibal ChamounLebanese American University, School of Pharmacy, Byblos, Lebanon.ORCID https://orcid.org/0000-0002-0987-296X
Myriam AudiLebanese American University, School of Pharmacy, Byblos, Lebanon.
Yasmina YaredHopital Libanais Geitaoui, Beirut, Lebanon.
Pascale SalamehLebanese University, Beirut, Lebanon.
Lebanese American University · LBAmerican University of Beirut Medical Center · LBLebanese Hospital Geitaoui-University Medical Center · LBLebanese University · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe evaluated the effect of chronic use of statins based on C-reactive protein (CRP) levels and hospital length of stay (LOS) in patients admitted with community-acquired pneumonia (CAP).

methodsWe conducted a retrospective study over 12 months at a teaching hospital in Lebanon comparing patients with CAP taking chronic statins with patients not taking statins. Included patients with CAP were older than age 18 years and had two CRP level measures during hospitalization. CURB-65 criteria were used to assess the severity of pneumonia. A decrease in CRP levels on days 1 and 3, LOS, and normalization of fever were used to assess the response to antibiotics.

resultsSixty-one patients were taking statins and 90 patients were not taking statins. Patients on statins had significantly more comorbid conditions; both groups had comparable CURB-65 scores. In both groups, no statistically significant difference was seen for the decrease in CRP level on days 1 and 3 and LOS. No difference in days to normalization of fever was detected in either group.

conclusionNo association was found between the chronic use of statins and CRP levels, LOS, or days to fever normalization in patients with CAP.

Indexed as

Community-Acquired InfectionsHydroxymethylglutaryl-CoA Reductase InhibitorsPneumoniaAdolescentHospitalizationHumansLength of StayRetrospective StudiesSeverity of Illness IndexHydroxymethylglutaryl-CoA Reductase InhibitorsAnti-inflammatoryclinical outcomescommunity-acquired pneumoniaC-reactive proteinmacrolidesnormalizationstatins

Identifiers

PMID32780619
PMCPMC7557788
OpenAlexW3048580817

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.