Evidence map›Paper›PMID 32780173›Full record

ArticleInternational urogynecology journal2021

Body mass index influences the risk of reoperation after first-time surgery for pelvic organ prolapse. A Danish cohort study, 2010-2016.

Vibeke Weltz, Rikke Guldberg, Michael Due Larsen, Gunnar Lose

Abstract read
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In one paragraph

Article in International urogynecology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Vibeke WeltzDepartment of Obstetrics and Gynaecology, Herlev University Hospital, Borgmester Ib Juuls vej 21, DK 2730, Herlev, Denmark. Vibeke.Weltz@regionh.dk.ORCID https://orcid.org/0000-0001-6169-3590
Rikke GuldbergDepartment of Obstetrics and Gynaecology, Aarhus University Hospital, Aarhus, Denmark.
Michael Due LarsenCenter for Clinical Epidemiology, Odense University Hospital, Denmark and Department of Clinical and Molecular Medicine Norwegian University of Science and Technology, Trondheim, Norway.ORCID https://orcid.org/0000-0002-0623-2481
Gunnar LoseDepartment of Obstetrics and Gynaecology, Herlev University Hospital, Borgmester Ib Juuls vej 21, DK 2730, Herlev, Denmark.
Herlev Hospital · DKAarhus University Hospital · DKNorwegian University of Science and Technology · NO

Funding

PROCRIN R1-007
6 · The paper itself

Abstract

introduction and hypothesisThe aims of this study were to evaluate the impact of body mass index (BMI) on the risk of reoperation for pelvic organ prolapse (POP) up to 5 years after first-time surgery. MATERIALS AND

methodsThis nationwide register-based study includes first-time POP surgery in 2010 through 2016. The cumulative incidence proportions of reoperation were analyzed in a Cox regression model and described using Kaplan-Meier plots stratified in BMI categories.

resultsA total of 28,533 first-time procedures were performed in 22,624 women; 76.6% had single-compartment repair. The 1- and 5-year reoperation rate within the same compartment was 2.6% and 6.1% respectively for women with BMI < 25, and for women with BMI > 35 it was 3.7% and 11.2 respectively. In the anterior compartment there was a significantly increased adjusted hazard ratio for reoperation in the same compartment with increasing BMI (reference group BMI < 25), BMI 30-34.9 with an aHR = 1.34 (CI 95% 1.04-1.71) and BMI ≥ 35 aHR = 1.77 (CI 95% 1.17-2.67). The 1- and 5-year reoperation rate in an adjacent compartment was 0.6% and 1.6% respectively for women with BMI < 25, and for women with BMI > 35 it was 1.0% and 4.4 respectively. For reoperation in an adjacent compartment the adjusted results were BMI 30-34.9 aHR = 1.64 (95% CI 1.05-2.56) and BMI > 35 aHR = 2.64 (95% CI 1.36-5.14) when the first-time operation was in the anterior compartment.

conclusionsIf the woman had BMI > 35 and first-time surgery was in the anterior compartment, she had an almost doubled risk of reoperation within 5 years both in the same compartment and in an adjacent compartment compared to women with BMI < 35. In the apical and posterior compartment there was a trend towards increasing risk of reoperation with increasing BMI, although with a broad confidence interval.

Indexed as

Gynecologic Surgical ProceduresPelvic Organ ProlapseBody Mass IndexCohort StudiesDenmarkFemaleHumansReoperationBody mass indexPelvic organ prolapseReoperationSurgery

Identifiers

PMID32780173
OpenAlexW3048730110

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.