Evidence map›Paper›PMID 32780172›Full record

ArticleInternational urogynecology journal2021

Reoperation rate and outcomes following the placement of polypropylene mesh by the vaginal route for cystocele: very long-term follow-up.

Marie Vinchant, Iris Bitumba, Vincent Letouzey, Hervé Fernandez, Renaud de Tayrac, Xavier Deffieux

Abstract read
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In one paragraph

Article in International urogynecology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Endometrial SUSD2Journal of personalized medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Marie VinchantAssistance Publique Hôpitaux de Paris (APHP), GHU Sud, Hôpital Antoine Béclère, Service de Gynécologie-Obstétrique, 157 Rue de la porte de Trivaux, 92140, Clamart, France.
Iris BitumbaAssistance Publique Hôpitaux de Paris (APHP), GHU Sud, Hôpital Antoine Béclère, Service de Gynécologie-Obstétrique, 157 Rue de la porte de Trivaux, 92140, Clamart, France.
Vincent LetouzeyFaculté de Médecine, Université Montpellier-Nîmes, 30000, Nimes, France.
Hervé FernandezFaculté de Médecine, Université Paris-Saclay, 94270, Le Kremlin Bicêtre, France.
Renaud de TayracFaculté de Médecine, Université Montpellier-Nîmes, 30000, Nimes, France.
Xavier DeffieuxAssistance Publique Hôpitaux de Paris (APHP), GHU Sud, Hôpital Antoine Béclère, Service de Gynécologie-Obstétrique, 157 Rue de la porte de Trivaux, 92140, Clamart, France. xavier.deffieux@aphp.fr.ORCID http://orcid.org/0000-0001-7856-2853
Assistance Publique – Hôpitaux de Paris · FRUniversité de Montpellier · FRUniversité Paris-Saclay · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisThe aim was to evaluate the reoperation rate and outcomes in women who underwent transvaginal non-absorbable monofilament polypropylene mesh placement for the treatment of cystocele.

methodsThe retrospective cohort study included 63 patients who underwent transvaginal surgery using a synthetic polypropylene mesh (Gynemesh™) for cystocele. Patients were evaluated using a clinical examination (POP-Q) and validated questionnaires (PGI-I, PFDI-20, PFIQ-7) at 18 years of follow-up (median 18 years [IQR 16-19]). Cumulative death rate was 13 out of 63 (20%) and rate of total loss to follow-up was 21 out of 50 (42%). Finally, among the 63 women who underwent surgery, 29 completed maximum follow-up and 21 underwent a clinical examination.

resultsThe cumulative reoperation rate was 35% (22 out of 63). Three patients were reoperated on because of recurrence of pelvic organ prolapse. Among the 63 patients initially operated, vaginal mesh exposure occurred in 16 (25%) during follow-up and 11 women (17%) needed a reintervention for vaginal mesh exposure. One patient was reoperated on for bladder mesh exposure. Among the 29 women who completed follow-up, the overall postoperative improvement rate was 93% after 18 years (PGI-I: 1-3). Mean overall satisfaction rate was 80 out of 100. Functional success rate was 76% (22 out of 29) and anatomical success rate was 62% (13 out of 21). The median score of the POP-DI-6 was 4.1 (IQR: 0-11) and the median score of the PFDI-20 was 30.7 (IQR: 13-60) in the 29 women who completed maximum follow-up.

conclusionAt very long-term follow-up, the recurrence rate of cystocele following polypropylene mesh placement by the vaginal route remained low and the satisfaction rate was high. However, we found high cumulative reoperation and mesh exposure rates.

Indexed as

CystocelePelvic Organ ProlapseFemaleFollow-Up StudiesHumansPolypropylenesReoperationRetrospective StudiesSurgical MeshTreatment OutcomeVaginaPolypropylenesComplicationsCystoceleMeshPelvic organ prolapsePolypropyleneReintervention

Identifiers

PMID32780172
OpenAlexW3048781131

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.