Evidence map›Paper›PMID 32780158›Full record

SynthesisEuropean archives of psychiatry and clinical neuroscience2021

Meta-analysis of cognitive functioning in patients with psychotic disorders and obsessive-compulsive symptoms.

Lotte Dijkstra, Jentien Vermeulen, Lieuwe de Haan, Frederike Schirmbeck

Abstract readMeta-Analysis
In one paragraph

Synthesis in European archives of psychiatry and clinical neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lotte DijkstraDepartment of Psychiatry, Amsterdam UMC, University of Amsterdam, Meibergdreef 5, Amsterdam-Zuidoost, 1105 AZ, Amsterdam, The Netherlands.
Jentien VermeulenDepartment of Psychiatry, Amsterdam UMC, University of Amsterdam, Meibergdreef 5, Amsterdam-Zuidoost, 1105 AZ, Amsterdam, The Netherlands.
Lieuwe de Haan *Department of Psychiatry, Amsterdam UMC, University of Amsterdam, Meibergdreef 5, Amsterdam-Zuidoost, 1105 AZ, Amsterdam, The Netherlands.
Frederike Schirmbeck *Department of Psychiatry, Amsterdam UMC, University of Amsterdam, Meibergdreef 5, Amsterdam-Zuidoost, 1105 AZ, Amsterdam, The Netherlands. n.f.schirmbeck@amsterdamumc.nl.ORCID http://orcid.org/0000-0003-1700-0958

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obsessive-compulsive symptoms (OCS) in psychotic disorders are associated with unfavorable outcomes, whether this extends to cognitive function remains unclear. We conducted meta-analyses on several cognitive domains to investigate overall group differences between patients with a psychotic disorder and co-occurring OCS (OCS +) and those without OCS (OCS-). We used meta-regression to assess possible confounding effects. No overall associations between OCS + and OCS- in any of the 17 investigated cognitive domains were found. We predominantly found large heterogeneity in effect size and direction among studies. Post-hoc analyses of processing speed tasks not purely based on reaction-time showed worse performance in the OCS + group with a small effect size (SMD = - 0.190; p = 0.029). Meta-regression revealed advanced age was significantly correlated with worse performance of the OCS + group in processing speed (R

Indexed as

Cognition DisordersObsessive-Compulsive DisorderPsychotic DisordersCognitionComorbidityHumansSchizophreniaComorbidityNeurocognitiveNeuropsychologicalOCDSchizophrenia

Identifiers

PMID32780158
PMCPMC8119404

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.