ArticleInternational journal of laboratory hematology2020
Clinical and hematological characteristics of 88 patients with COVID-19.
Article in International journal of laboratory hematology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Identification of Parameters Representative of Immune Dysfunction in Patients with Severe and Fatal COVID-19 Infection: a Systematic Review and Meta-analysis.Clinical reviews in allergy & immunology · 2023Pooled it
- A systematic meta-analysis of immune signatures in patients with COVID-19.Reviews in medical virology · 2021Pooled it
- Nervous system diseases are associated with the severity and mortality of patients with COVID-19: a systematic review and meta-analysis.Epidemiology and infection · 2021Pooled it
- Hematological Indices in COVID-19 Patients with Rhinosinusitis Mucormycosis.Iranian journal of otorhinolaryngology · 2024Article
- Evaluation of Inflammatory Markers in Patients with COVID-19 Combined with Type 2 Diabetes Mellitus.Risk management and healthcare policy · 2024Article
- Neurological complications and effects of COVID-19: Symptoms and conceivable mechanisms.Brain hemorrhages · 2023Review
- CBC Differences between Survived and Deceased COVID-19 Patients: A Cohort Study.Medical journal of the Islamic Republic of Iran · 2023Article
- Routine hematology parameters in COVID-19: A predictor of disease severity and mortality.Journal of family medicine and primary care · 2022Article
- Heterogeneity and Risk of Bias in Studies Examining Risk Factors for Severe Illness and Death in COVID-19: A Systematic Review and Meta-Analysis.Pathogens (Basel, Switzerland) · 2022Review
- Immune Signature of COVID-19: In-Depth Reasons and Consequences of the Cytokine Storm.International journal of molecular sciences · 2022Review
- Combined Blood Indexes of Systemic Inflammation as a Mirror to Admission to Intensive Care Unit in COVID-19 Patients: A Multicentric Study.Journal of epidemiology and global health · 2022Article
- Comparative analysis of neutrophil to lymphocyte ratio and derived neutrophil to lymphocyte ratio with respect to outcomes of in-hospital coronavirus disease 2019 patients: A retrospective study.Frontiers in medicine · 2022Article
- COVID-19 and hematology findings based on the current evidences: A puzzle with many missing pieces.International journal of laboratory hematology · 2021Review
- Relationship between changes in the course of COVID-19 and ratio of neutrophils-to-lymphocytes and related parameters in patients with severeEpidemiology and infection · 2021Article
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- A new haematocytometric index: Predicting severity and mortality risk value in COVID-19 patients.PloS one · 2021Article
- COVID-19, leprosy, and neutrophils.PLoS neglected tropical diseases · 2021Article
- The Systemic Inflammation Index on Admission Predicts In-Hospital Mortality in COVID-19 Patients.Molecules (Basel, Switzerland) · 2020Article
- Clinical and hematological characteristics of 88 patients with COVID-19.International journal of laboratory hematology · 2020Article
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Authors and funding
9 authors.
Funding
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Abstract
introductionTo retrospectively analyze epidemiological, clinical and hematological characteristics of COVID-19 patients.
methodsThe demographic, symptoms, and physiological parameters of 88 patients were collected and analyzed. The performance of complete blood count (CBC) indexes for monitoring and predicting the severity of COVID-19 in patients was evaluated by analyzing and comparing CBC results among different COVID-19 patient groups.
resultsWhite blood cells (WBCs), the neutrophil percentage (Neu%), absolute neutrophil count (Neu#), and neutrophil-to-lymphocyte ratio (NLR) were significantly higher in the critical group than in the other three groups (P < .05), while the lymphocyte percentage (Lym%), monocyte percentage (Mon%), lymphocyte count (Lym#), and lymphocyte-to-monocyte ratio (LMR) were significantly lower in the critical group than in the other three groups (P < .05). WBCs, the Neu%, Neu#, NLR, and neutrophil-to-monocyte ratio (NMR) were significantly higher in the severe group than in the mild and moderate groups (P < .05), while the Lym% was significantly lower in the severe group than in the mild and moderate groups (P < .05). The Mon%, Lym#, and LMR were significantly lower in the severe group than in the moderate group (P < .05). Using receiver operating characteristic (ROC) curve analysis to differentiate severe and nonsevere patients, the areas under the curve (AUCs) for the NLR, Neu%, and Lym% were 0.733, 0.732, and 0.730, respectively. When differentiating critical patients from noncritical patients, the AUCs for the NLR, Neu%, and Lym% were 0.832, 0.831, and 0.831.
conclusionsThe NLR is valuable for differentiating and predicting patients who will become critical within 4 weeks after the onset of COVID-19.
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