Evidence map›Paper›PMID 32779613›Full record

ArticleJournal of clinical and experimental hematopathology : JCEH2020

Significant role of magnetic resonance imaging for the diagnosis and evaluation of cardiac amyloidosis in primary light chain amyloidosis.

Yasunobu Sekiguchi, Mutsumi Wakabayashi, Hiroko Iizuka, Haruko Takizawa, Keiji Sugimoto, Sakura Sakajiri, Tadaaki Inano, Yasutaka Fukuda, Yasuharu Hamano, Shigeki Tomita and 7 more

Abstract readCase Reports
In one paragraph

Article in Journal of clinical and experimental hematopathology : JCEH, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yasunobu SekiguchiDepartment of Hematology, Juntendo University Urayasu Hospital, Urayasu-shi, Japan.
Mutsumi WakabayashiDepartment of Hematology, Juntendo University Urayasu Hospital, Urayasu-shi, Japan.
Hiroko IizukaDepartment of Hematology, Juntendo University Urayasu Hospital, Urayasu-shi, Japan.
Haruko TakizawaDepartment of Hematology, Juntendo University Urayasu Hospital, Urayasu-shi, Japan.
Keiji SugimotoDepartment of Hematology, Juntendo University Urayasu Hospital, Urayasu-shi, Japan.
Sakura SakajiriDepartment of Hematology, Juntendo University Urayasu Hospital, Urayasu-shi, Japan.
Tadaaki InanoDepartment of Hematology, Juntendo University Hospital, Bunkyo-ku, Japan.
Yasutaka FukudaDepartment of Hematology, Juntendo University Hospital, Bunkyo-ku, Japan.
Yasuharu HamanoDepartment of Hematology, Juntendo University Hospital, Bunkyo-ku, Japan.
Shigeki TomitaDepartment of Pathology, Juntendo University Urayasu Hospital, Urayasu-shi, Japan.
Hiroshi IzumiDepartment of Pathology, Juntendo University Urayasu Hospital, Urayasu-shi, Japan.
Hiroyuki IsogaiDepartment of Cardiology, Juntendo University Urayasu Hospital, Urayasu-shi, Japan.
Mitsuo OkuboDepartment of Transfusion Medicine, Juntendo University Urayasu Hospital, Urayasu-shi, Japan.
Noriko NakamuraDepartment of Laboratory Medicine, Juntendo University Urayasu Hospital, Urayasu-shi, Japan.
Tomohiro SawadaDepartment of Laboratory Medicine, Juntendo University Urayasu Hospital, Urayasu-shi, Japan.
Kimihiro MatsumotoDepartment of Internal Medicine, Tokyo Dental University Ichikawa General Hospital, Ichikawa-shi, Japan.
Masaaki NoguchiDepartment of Hematology, Juntendo University Urayasu Hospital, Urayasu-shi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 47-year-old male with macroglossia presented with dyspnea on effort and chest pain at rest. Cardiac MRI revealed diffuse global subendocardial late gadolinium enhancement below the left ventricular endocardium and a dark blood pool of intracardiac contrast medium. Tongue biopsy revealed amyloid deposition, which was limited in the myocardium. He was diagnosed with primary light chain amyloidosis. His condition was stage I according to the Mayo Clinic staging system. He underwent autologous peripheral blood stem cell transplantation. On Day 10, he developed chest pain and died suddenly on Day 11. Postmortem examination revealed amyloid deposition throughout the heart.

Indexed as

AmyloidosisHeartHumansMagnetic Resonance ImagingMaleMiddle AgedMyocardiumStem Cell Transplantationautologous peripheral blood stem cell transplantcardiac amyloidosiscardiac biomarkercardiac MRIprimary AL amyloidosis

Identifiers

PMID32779613
PMCPMC7596909

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.