Evidence map›Paper›PMID 32779280›Full record

ArticleDermatologic therapy2020

Maculopapular eruptions associated to COVID-19: A subanalysis of the COVID-Piel study.

Alba Català, Cristina Galván-Casas, Gregorio Carretero-Hernández, Pedro Rodríguez-Jiménez, Daniel Fernández-Nieto, Ana Rodríguez-Villa, Íñigo Navarro-Fernández, Ricardo Ruiz-Villaverde, Daniel Falkenhain-López, Mar Llamas-Velasco and 14 more

Abstract read
In one paragraph

Article in Dermatologic therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Cutaneous Manifestations of SARS-CoV-2 Infection.American journal of clinical dermatology · 2022
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
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  17. Article
  18. Erythema Multiforme and COVID-19: What Do We Know?Medicina (Kaunas, Lithuania) · 2021
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Alba CatalàHospital Plató, Barcelona, Spain.ORCID https://orcid.org/0000-0001-9916-6411
Cristina Galván-CasasHospital Universitario de Móstoles, Madrid, Spain.
Gregorio Carretero-HernándezHospital Universitario de Gran Canaria Dr. Negrín, Las Palmas, Spain.
Pedro Rodríguez-JiménezHospital Universitario de la Princesa, Madrid, Spain.ORCID https://orcid.org/0000-0002-7061-3027
Daniel Fernández-NietoHospital Universitario Ramón y Cajal, Madrid, Spain.ORCID https://orcid.org/0000-0003-4461-1770
Ana Rodríguez-VillaHospital Universitario Príncipe de Asturias, Madrid, Spain.
Íñigo Navarro-FernándezHospital Universitario "Marqués de Valdecilla", Santander, Spain.
Ricardo Ruiz-VillaverdeHospital Universitario Clínico San Cecilio, Granada, Spain.ORCID https://orcid.org/0000-0002-0381-6174
Daniel Falkenhain-LópezHospital Universitario 12 de Octubre, Madrid, Spain.
Mar Llamas-VelascoHospital Universitario de la Princesa, Madrid, Spain.ORCID https://orcid.org/0000-0002-1187-1341
Lucía Carnero-GonzalezHUA Santiago, Vitoria-Gasteiz, Spain.
Juan García-GavinGavín Dermatólogos, Vigo, Spain.
Ofelia BaniandrésHospital General Universitario Gregorio Marañón, Madrid, Spain.
Carlos González-CruzHospital Universitari Vall d'Hebron, Barcelona, Spain.
Víctor Morillas-LahuertaHospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain.
Xavier CubiróHospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Ignasi FiguerasHospital Universitario de Bellvitge, Hospitalet de Llobregat, Barcelona, Spain.
Gerald Selda-EnriquezHospital Universitario Ramón y Cajal, Madrid, Spain.ORCID https://orcid.org/0000-0002-7771-2765
Xavier Fustà-NovellAlthaia, Xarxa Assistencial Universitària de Manresa, Manresa, Barcelona, Spain.
Mónica Roncero-RiescoComplejo Asistencial Universitario de Salamanca, Salamanca, Spain.
Patrícia Burgos-BlascoHospital Universitario Ramón y Cajal, Madrid, Spain.
Jorge RomaníConsorci Sanitari Parc Taulí, Sabadell, Barcelona, Spain.ORCID https://orcid.org/0000-0002-5161-5078
Joaquim Solà-OrtigosaHospital General de Granollers, Barcelona, Spain.ORCID https://orcid.org/0000-0002-7911-8428
Ignacio García-DovalResearch Unit, Fundación Piel Sana Academia Española de Dermatología y Venereología, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A previous study has defined the maculopapular subtype of manifestations of COVID-19. The objective of our study was to describe and classify maculopapular eruptions associated with COVI-19. We carried out a subanalysis of the maculopapular cases found in the previous cross-sectional study. Using a consensus, we defined seven clinical patterns. We described patient demographics, the therapy received by the patient and the characteristics of each pattern. Consensus lead to the description of seven major maculopapular patterns: morbilliform (45.5%), other maculopapular (20.0%), purpuric (14.2%), erythema multiforme-like (9.7%), pytiriasis rosea-like (5.7%), erythema elevatum diutinum-like (2.3%), and perifollicular (2.3%). In most cases, maculopapular eruptions were coincident (61.9%) or subsequent (34.1%) to the onset of other COVID-19 manifestations. The most frequent were cough (76%), dyspnea (72%), fever (88%), and astenia (62%). Hospital admission due to pneumonia was frequent (61%). Drug intake was frequent (78%). Laboratory alterations associated with maculo-papular eruptions were high C-reactive protein, high D-Dimer, lymphopenia, high ferritin, high LDH, and high IL-6. The main limitation of our study was the impossibility to define the cause-effect relationship of each pattern. In conclusion, we provide a description of the cutaneous maculopapular manifestations associated with COVID-19. The cutaneous manifestations of COVID-19 are wide-ranging and can mimic other dermatoses.

Indexed as

AdolescentAdultAgedAged, 80 and overAntiviral AgentsCOVID-19COVID-19 Drug TreatmentCross-Sectional StudiesFemaleHost-Pathogen InteractionsHumansMaleMiddle AgedRisk FactorsSARS-CoV-2SkinAntiviral AgentscoronavirusCOVID-19cutaneous manifestationsskin

Identifiers

PMID32779280
PMCPMC7436694

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.