ArticleInternational journal of clinical oncology2020
Accuracy of histological grades from intraoperative frozen-section diagnoses of soft-tissue tumors.
Article in International journal of clinical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Lessons in balancing function with oncological control in a destructive lumbosacral tumor of uncertain pathology: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Intraoperative Peripheral Frozen Margin Assessment in Soft Tissue Sarcoma.Journal of surgical oncology · 2025Article
- Toward the use of diffuse reflection spectroscopy for intra-operative tissue discrimination during sarcoma surgery.Journal of biomedical optics · 2024Article
- Application of Indocyanine Green Fluorescence Imaging in Assisting Biopsy of Musculoskeletal Tumors.Cancers · 2023Article
- Looking for a perfect match: multimodal combinations of Raman spectroscopy for biomedical applications.Journal of biomedical optics · 2021Review
- Review
- Periureteral Liposarcoma Causes of Hydroureter and Hydronephrosis: An Unpredictable Diagnosis.Gynecology and minimally invasive therapyArticle
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14 authors.
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Abstract
backgroundFor excised tumor specimens, histological grades can differ between the biopsy diagnosis and the final diagnosis.
methodsWe retrospectively investigated the diagnostic accuracies of histological grades for frozen-section and permanent-section diagnoses from patients with soft-tissue tumors. Frozen-section, permanent-section, and final diagnoses were classified as benign tumors/tumor-like lesions, intermediate malignancies, or malignant tumors. Diagnostic accuracies of the histological grades from the frozen and permanent sections were evaluated by comparing the final diagnoses for the resected specimens.
resultsThe diagnostic accuracies of the histological grades for the frozen- and permanent-section diagnoses were 95% (387/408 lesions) and 97% (395/408 lesions), respectively. Among the tumor types, the diagnostic accuracies of the histological grades for the frozen-section and permanent-section diagnoses were 84% and 87% for adipocytic tumors, 87% and 91% for fibroblastic/myofibroblastic tumors, 99% and 100% for nerve-sheath tumors, 98% and 98% for fibrohistiocytic tumors, 90% and 98% for tumors of uncertain differentiation, 100% and 100% for vascular tumors, and 97% and 98% for other tumors, respectively.
conclusionsHistological grades from frozen-section diagnoses yielded low diagnostic accuracies in adipocytic and fibroblastic/myofibroblastic tumors. Treatment should be planned based on permanent-section diagnosis and radiological findings for these tumors.
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