ArticleClinical oral investigations2021
Subgingival microflora in adolescent females with polycystic ovary syndrome and its association with oral hygiene, gingivitis, and selected metabolic and hormonal parameters.
Article in Clinical oral investigations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 26 citations in OpenAlex.
- The Gut-Reproduction-Oral-Immune Axis: Microbial Dysbiosis as a Shared Driver in Polycystic Ovary Syndrome and Endometriosis.Current microbiology · 2026Review
- Serum BDNF as an integrative neuro-immunometabolic marker in adolescent polycystic ovary syndrome: divergent dietary and inflammatory associations across weight phenotypes.Frontiers in nutrition · 2026Article
- Association between oral microbial shifts and polycystic ovary syndrome: a systematic review.Journal of oral microbiology · 2026Review
- Subgingival Microbiome Profiles in Bulgarian Children Aged 10-14 with Gingival Inflammation and Healthy Periodontium: A Targeted PCR Study.Microorganisms · 2025Article
- The Association Between Periodontal Disease and Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.Dentistry journal · 2025Review
- Article
- Association between the severity of gingival inflammation and microbial findings in children.Frontiers in dental medicine · 2025Article
- Impact of Polycystic Ovary Syndrome on Periodontal Status of Women of Adolescent and Adult Age Groups: A Cross-Sectional Study.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2024Article
- Comparative analysis of serum and saliva samples using Raman spectroscopy: a high-throughput investigation in patients with polycystic ovary syndrome and periodontitis.BMC women's health · 2023Article
- Cytomorphometric Analysis of Oral Buccal Mucosa of Dental Colleges' Students in Sulaimani City.Diagnostics (Basel, Switzerland) · 2023Article
- Causal relationship between PCOS and related sex hormones with oral inflammatory diseases: a bidirectional Mendelian randomization study.Frontiers in endocrinology · 2023Article
- Bidirectional association between polycystic ovary syndrome and periodontal diseases.Frontiers in endocrinology · 2023Review
- Association of Macronutrients Composition, Physical Activity and Serum Androgen Concentration in Young Women with Polycystic Ovary Syndrome.Nutrients · 2021Observational
- Correlation of Periodontal Bacteria with Chronic Inflammation Present in Patients with Metabolic Syndrome.Biomedicines · 2021Article
- Dietary and Physical Activity Habits in Adolescent Girls with Polycystic Ovary Syndrome (PCOS)-HAstudy.Journal of clinical medicine · 2021Article
- Association between metabolic and hormonal profile, proinflammatory cytokines in saliva and gingival health in adolescent females with polycystic ovary syndrome.BMC oral health · 2021Article
- Article
- Sex Steroid Hormones as a Balancing Factor in Oral Host Microbiome Interactions.Frontiers in cellular and infection microbiology · 2021Review
- Risk Factors of Overweight and Obesity Related to Diet and Disordered Eating Attitudes in Adolescent Girls with Clinical Features of Polycystic Ovary Syndrome.Journal of clinical medicine · 2020Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectivesResearch studies suggest that polycystic ovary syndrome (PCOS) may influence the composition of the oral microflora in women. This study aimed to investigate factors affecting the number of selected periopathogens in a young cohort of females with PCOS and to assess the association between oral hygiene, subgingival microbiome, gingival health, and metabolic and hormonal parameters. MATERIALS AND
methodsThirty-two subjects with PCOS and twenty-three healthy controls aged 15-19 years were examined periodontally by a calibrated dentist. A real-time PCR method was used for the identification of 9 subgingival microorganisms. Subjects with PCOS underwent blood tests for determination of FSH, LH, total testosterone, DHEA-S, estradiol, SHBG, fasting glucose, fasting insulin, and lipid profile.
resultsGingival index (GI), the proportion of bleeding sites (BOP%), probing depth (PD), and plaque index (PLI) did not differ significantly between cases and healthy age-mates. The control group had significantly higher levels of Peptostreptococcus micros and substantially greater percentage of subjects infected by Treponema denticola. Capnocytophaga gingivalis count was positively correlated with the level of estradiol, while the concentration of HDL-C was negatively correlated with the number of Aggregatibacter actinomycetemcomitans and orange complex bacteria.
conclusionsPCOS in young patients was not associated with higher pathogenicity of subgingival biofilms. CLINICAL RELEVANCE: Further studies are needed to explain the relationship between hormonal and metabolic abnormalities, subgingival microflora, and periodontal health in patients with PCOS.
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