ArticleScientific reports2020
Associations of childhood experiences with event-related potentials in adults with autism spectrum disorder.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Systematic Review and Meta-Analysis of Mismatch Negativity in Autism: Insights Into Predictive Mechanisms.Autism research : official journal of the International Society for Autism Research · 2025Pooled it
- The Many Faces of Child Abuse: How Clinical, Genetic and Epigenetic Correlates Help Us See the Full Picture.Children (Basel, Switzerland) · 2025Review
- Microstructure Abnormalities of Diffusion Tensor Imaging Measures in First-Episode, Treatment-Naïve Adolescents With Major Depressive Disorder: An Integrated AFQ and TBSS Study.Brain and behavior · 2025Article
- Preliminary observations on the associations between sensory processing abnormalities and event-related potentials in adults with autism spectrum disorder.PCN reports : psychiatry and clinical neurosciences · 2024Article
- Microstructure abnormalities of the diffusion quantities in children with attention-deficit/hyperactivity disorder: an AFQ and TBSS study.Frontiers in psychiatry · 2023Article
- Association of adverse childhood experiences and cortical neurite density alterations with posttraumatic stress disorder symptoms in autism spectrum disorder.Frontiers in psychiatry · 2023Article
- P300 Event-Related Potentials Mediate the Relationship Between Child Physical Abuse and Externalizing Behavior.Frontiers in psychology · 2021Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Childhood maltreatment is defined as experiencing of physical, emotional and sexual abuse and neglect in childhood. Maltreatment in childhood leads to substantial psychosocial problems later in life in the general population. Individuals with autism spectrum disorder (ASD) have a higher risk of experiencing stressful and traumatic events, such as maltreatment, during childhood. Although childhood maltreatment reportedly leads to psychosocial problems in adults with ASD, the biological associations between childhood experiences and brain function in this population remain understudied. Here, we evaluated the relationships between childhood experiences and event-related potential (ERP) components during the auditory odd-ball task in adults with ASD (N = 21) and typically developed (TD) individuals (N = 22). We found that the higher the severity of sexual abuse, the larger the amplitude of P300 at Fz, Cz, C3, and C4 in individuals with ASD. Conversely, the severity of child maltreatment was associated with P300 latency at Cz and C3 in TD individuals. Moreover, full IQ was significantly associated with the MMN amplitude at Fz, Cz, C3, and C4 in TD individuals. These findings provide the first evidence that ERPs could be used to study the impacts childhood experiences on the brain of individuals with ASD and that childhood sexual abuse has salient impacts on brain function in this population.
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