Evidence map›Paper›PMID 32778367›Full record

ArticleEuropean neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology2020

Predictors of serious suicidal behavior in late-life depression.

Katalin Szanto, Hanga Galfalvy, Laura Kenneally, Rebeka Almasi, Alexandre Y Dombrovski

Open access · greenAbstract read
In one paragraph

Article in European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
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  5. Associations of Self-Reported Deterrents to Suicide Attempts in Depressed Older Adults.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2025
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  12. Life-Satisfaction, Engagement, Mindfulness, Flourishing, and Social Support: Do they Predict Depression, Suicide Ideation, and History of Suicide Attempt in Late Life?The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2023
    Article
  13. Can Emotional Well-Being Maintain Health and Prevent Suicide in Later Life? A National Priority for Research.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Katalin SzantoUniversity of Pittsburgh, Pittsburgh, PA, 15213, USA. Electronic address: szantok@upmc.edu.
Hanga GalfalvyColumbia University, New York, NY, 10032, USA.
Laura KenneallyVirginia Consortium Program in Clinical Psychology, Norfolk, VA, 23504, USA.
Rebeka AlmasiCarnegie Mellon University, Pittsburgh, PA, 15213, USA.
Alexandre Y DombrovskiUniversity of Pittsburgh, Pittsburgh, PA, 15213, USA.
University of Pittsburgh · USCarnegie Mellon University · USColumbia University · USVirginia Clinical Research · US

Funding

PSYCHOBIOLOGY OF SUICIDAL BEHAVIOR IN BPDR01MH048463 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Alexandre Y. Dombrovski · 1992 to 2026
$13.9M
Short Term Variability in Affect and Rest Activity Rhythms in Long Term Chronic and Highly Variable Suicidal Ideation in Depressed Older AdultsR01MH085651 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HANGA CSILLA GALFALVY, Swathi Gujral · 2010 to 2026
$9.6M
Reward Learning in Late-Life Suicidal BehaviorR01MH100095 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Alexandre Y. Dombrovski · 2014 to 2026
$6.8M
NIMH NIH HHS R01 MH048463NIMH NIH HHS R01 MH085651NIMH NIH HHS R01 MH100095
6 · The paper itself

Abstract

The present study aimed to identify pathways to suicidal behavior in late life that can guide identification of those most at risk and improve treatment. In a longitudinal study of late-life depression, we prospectively assessed risk factors specifically associated with fatal and near-fatal as compared to less lethal suicidal behavior. We enrolled 401 participants (age 66+9.9): 311 with unipolar non-psychotic depression and 90 non-psychiatric controls. The median follow-up was 5.4 years. Results indicated that history of suicide attempt predicted a two-fold increase in the risk of dying from natural causes. In univariate models, male gender, higher income, current depression and current and worst lifetime suicidal ideation severity, cognitive control deficits, and low levels of non-planning impulsivity predicted fatal and near-fatal suicidal behavior. In contrast, incident less lethal suicidal behavior was mostly associated with maladaptive personality traits, impulsivity, and severity of psychiatric illness in univariate models. In multipredictor models, male gender, worst lifetime suicidal ideation, and deficits in cognitive control independently predicted fatal/near-fatal suicidal behavior, while introversion, history of suicide attempt, and earlier age of onset of depression predicted less lethal suicidal behavior. While clinicians may be familiar with suicide risk factors identified in younger samples such as dysfunctional personality, impulsivity, and co-morbid substance use, in late life these characteristics only pertain to lower-lethality suicidal behavior. Cognitive control deficits, which likely play a greater role in old age, predict serious suicidal behavior.

Indexed as

Suicidal IdeationAgedDepressionFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleMiddle AgedPilot ProjectsPredictive Value of TestsProspective StudiesSuicide, AttemptedCognitionCognitive controlIncident suicidal behaviorLate-life depressionPersonality

Identifiers

PMID32778367
PMCPMC7655527
OpenAlexW3048154532

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.