Evidence map›Paper›PMID 32778226›Full record

ArticleAnnals of epidemiology2020

Spatiotemporal distribution of autism spectrum disorder prevalence among birth cohorts during 2000-2011 in Israel.

Hadas Magen-Molho, Ruthie Harari-Kremer, Ofir Pinto, Itai Kloog, Michael Dorman, Hagai Levine, Marc G Weisskopf, Raanan Raz

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In one paragraph

Article in Annals of epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hadas Magen-MolhoFaculty of Medicine, Braun School of Public Health and Community Medicine, The Hebrew University - Hadassah, Jerusalem, Israel; The Advanced School for Environmental Studies, The Hebrew University, Jerusalem, Israel. Electronic address: hadas.molho@mail.huji.ac.il.
Ruthie Harari-KremerFaculty of Medicine, Braun School of Public Health and Community Medicine, The Hebrew University - Hadassah, Jerusalem, Israel; The Advanced School for Environmental Studies, The Hebrew University, Jerusalem, Israel.
Ofir PintoIsrael National Insurance Institute, Jerusalem, Israel.
Itai KloogDepartment of Geography and Environmental Development, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Michael DormanDepartment of Geography and Environmental Development, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Hagai LevineFaculty of Medicine, Braun School of Public Health and Community Medicine, The Hebrew University - Hadassah, Jerusalem, Israel.
Marc G WeisskopfDepartment of Epidemiology, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Raanan RazFaculty of Medicine, Braun School of Public Health and Community Medicine, The Hebrew University - Hadassah, Jerusalem, Israel.

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
Air Pollution and Autism in Israel: A Population-Wide StudyR21ES026900 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI WEISSKOPF, MARC G · 2016 to 2017
$391k
NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R21 ES026900
6 · The paper itself

Abstract

purposeStudies indicate an apparent sharp increasing trend in autism spectrum disorder (ASD) incidence and prevalence worldwide. This nationwide study aims at depicting ASD prevalence distribution in Israel in both space and time.

methodsBased on data from Israel National Insurance Institute, the study population included all children born in Israel 2000-2011 (n = 1,786,194), of whom 11,699 (0.655%) were subsequently diagnosed with ASD (until December 31, 2016). Prevalence was calculated and mapped by dividing the number of ASD cases within each year of birth by the number of births during that year, for each spatial unit, and similarly for several spatiotemporal levels of aggregation.

resultsASD prevalence varies substantially across different geographic areas in Israel, with considerably higher prevalence concentrated in central Israel. Strong associations were found between locality-level socioeconomic index, ethnicity, and peripherality and ASD prevalence, and even after adjustment for them, excess prevalence for ASD still persisted in certain localities. No spatial dependence of prevalence, with and without adjustment for the locality-level variables, was found (Moran's I = -0.000546, -0.00335, respectively).

conclusionsOur findings provide important insights regarding health disparities affecting ASD diagnosis, directing further health policy intervention and further research.

Indexed as

Health Status DisparitiesResidence CharacteristicsAdolescentAutism Spectrum DisorderChildCohort StudiesEthnicityFemaleGeographic Information SystemsHumansIncidenceIsraelMalePopulation SurveillanceSpatio-Temporal AnalysisAutism spectrum disorderGeographical information systemsIsraelPrevalenceSpatial distribution

Identifiers

PMID32778226
PMCPMC7419709

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.