Evidence map›Paper›PMID 32778158›Full record

ArticleTrials2020

Using electroacupuncture to recover muscle strength in patients with knee osteoarthritis after total knee arthroplasty: a study protocol for a double-blinded, randomized, and placebo-controlled trial.

Hui Xu, Bingxin Kang, Yulin Li, Jun Xie, Songtao Sun, Sheng Zhong, Chenxin Gao, Xirui Xu, Chi Zhao, Guowei Qiu and 1 more

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Electroacupuncture combined with nutritional intervention for gastrointestinal cancer-related sarcopenia: a randomized controlled trial using ultrasonographic indices.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Hui XuDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, 200050, China.
Bingxin KangDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, 200050, China.
Yulin LiShanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Jun XieDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, 200050, China.
Songtao SunDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, 200050, China.
Sheng ZhongDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, 200050, China.
Chenxin GaoDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, 200050, China.
Xirui XuDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, 200050, China.
Chi ZhaoDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, 200050, China.
Guowei QiuDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, 200050, China.
Lianbo XiaoDepartment of Joint Orthopaedics, Guanghua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, 200050, China. xiao_lianbo@163.com.ORCID http://orcid.org/0000-0003-4226-6002
Shanghai University of Traditional Chinese Medicine · CN

Funding

Shanghai Municipal Health and Family Planning Commission Program ZY (2018-2020) -FWTX-6023
6 · The paper itself

Abstract

backgroundTotal knee arthroplasty (TKA) is a gold standard for patients with terminal term gonarthrosis for reducing pain, correcting deformities, and regaining stability. However, post-TKA muscle strength recovery is often difficult. Although electroacupuncture (EA) enhances lower extremity muscle strength of the lower extremity, there is limited evidence regarding its effect on lower extremity muscle strength in post-TKA patients. Consequently, this trial intends to evaluate the efficacy of post-TKA EA on the recovery of lower extremity muscle strength, specifically, during the early post-TKA period. METHODS/

designThis is a double-blinded, randomized, and controlled trial. It will be conducted between August 2020 and December 2020. Ninety-four participants with KOA who have undergone unilateral TKA will be randomized into a treatment (EA) group and a control (sham EA) group. The former and latter groups will receive EA and sham EA, respectively, at ST37, ST36, SP10, and SP9 acupoints. The participants will undergo ten treatment sessions over 2 weeks (5 sessions per week). The primary outcomes will include changes in muscle strength and the Hospital for Special Surgery score at the second week from baseline (pre-op 1 day or POD 3). The secondary outcomes will include a 4-m walk test, numerical rating scale score, the Hamilton Anxiety Scale score, and additional analgesia use. Additional outcomes will include the incidence of analgesia-related side effects and the participant satisfaction rate. Participant blinding will also be assessed where they will be asked to guess whether they received EA after the latest intervention. Adverse EA events will be documented and assessed throughout the trial. DISCUSSION: EA is helpful for post-TKA recovery and enhancement of lower limb muscle strength.

trial registrationChinese Clinical Trial Registry ChiCTR1900027806 . Registered on 29 November 2019.

Indexed as

Arthroplasty, Replacement, KneeElectroacupunctureMuscle StrengthOsteoarthritis, KneeDouble-Blind MethodHumansRandomized Controlled Trials as TopicTreatment OutcomeElectroacupunctureKnee osteoarthritisStudy protocolTotal knee arthroplasty

Identifiers

PMID32778158
PMCPMC7418422
OpenAlexW3048773688

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.