ArticleJournal of nanobiotechnology2020
Simultaneous and sensitive determination of ascorbic acid, dopamine and uric acid via an electrochemical sensor based on PVP-graphene composite.
Article in Journal of nanobiotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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44 citing papers in PubMed.
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- Size-Dependent Electrochemical Response and Dopamine Sensitivity of Aptamer-Modified Printed Gold Nanoparticle Structures.ACS omega · 2026Article
- Functional Nanomaterial-Based Electrochemical Biosensors Enable Sensitive Detection of Disease-Related Small-Molecule Biomarkers for Diagnostics.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Oral targeting tilianin nanoplatform mitigates atherosclerosis through promoting macrophage phagocytosis and anti-inflammation.Materials today. Bio · 2025Article
- Comparative Assessment of Gold and Carbon Nanoparticles as Tags for Lateral Flow Immunoassay of Fenpropathrin in Green Tea.Foods (Basel, Switzerland) · 2025Article
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- Direct Electrochemical Detection of Tyramine in Beer Samples Using a MWCNTs Modified GCE.Sensors (Basel, Switzerland) · 2025Article
- Copper Nanoclusters Anchored on Crumpled N-Doped MXene for Ultra-Sensitive Electrochemical Sensing.Sensors (Basel, Switzerland) · 2025Article
- Reduced graphene oxide/zinc oxide composite as an electrochemical sensor for acetylcholine detection.Scientific reports · 2024Article
- Self-assembled ordered AuNRs-modified electrodes for simultaneous determination of dopamine and topotecan with improved data reproducibility.Mikrochimica acta · 2024Article
- The Simultaneous Detection of Dopamine and Uric Acid In Vivo Based on a 3D Reduced Graphene Oxide-MXene Composite Electrode.Molecules (Basel, Switzerland) · 2024Article
- ZnO-CeOMolecules (Basel, Switzerland) · 2024Article
- Highly sensitive and simultaneous detection of ascorbic acid, dopamine, and uric acid using Pt@g-CiScience · 2024Article
- Novel Enzymatic Biosensor Utilizing a MoSACS omega · 2023Article
- Progress in the Mechanism of the Effect of FeMolecules (Basel, Switzerland) · 2023Review
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- Investigation of the photoactivation effect of TiOHeliyon · 2023Article
- Recent advances in electrochemical sensors and biosensors for monitoring drugs and metabolites in pharmaceutical and biological samples.ADMET & DMPK · 2023Review
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A method with high sensitivity, good accuracy and fast response is of ever increasing importance for the simultaneous detection of AA, DA and UA. In this paper, a simple and sensitive electrochemical sensor, which based on the polyvinylpyrrolidone (PVP)-graphene composite film modified glassy carbon electrode (PVP-GR/GCE), was presented for detecting ascorbic acid (AA), dopamine (DA) and uric acid (UA) simultaneously. The PVP-GR/GCE has excellent electrocatalytic activity for the oxidation of AA, DA and UA. The second-order derivative linear sweep voltammetry was used for the electrochemical measurements. The peak potential differences of DA-AA, DA-UA, and UA-AA (measured on the PVP-GR/GCE) were 212, 130 and 342 mV respectively. Besides, the over potential of AA, DA and UA reduced obviously, so did the peak current increase. Under the optimum conditions, the linear ranges of AA, DA and UA were 4.0 μM-1.0 mM, 0.02-100 μM, and 0.04-100 μM, respectively. The detection limits were 0.8 μM, 0.002 μM and 0.02 μM for AA, DA, and UA. The electrochemical sensor presented the advantages of high sensitivity and selectivity, excellent reproducibility and long-term stability. Furthermore, the sensor was successfully applied to the analysis of real samples.
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