Evidence map›Paper›PMID 32778060›Full record

ArticleBMC infectious diseases2020

Gaps in the care cascade for screening and treatment of refugees with tuberculosis infection in Middle Tennessee: a retrospective cohort study.

Adoma Manful, Leslie Waller, Ben Katz, Jason Cummins, Jon Warkentin, Billy Reagon, Joanna Shaw-Kaikai, Yuwei Zhu, Yuri F van der Heijden

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.1field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Uncovering Household Tuberculosis Infection Testing and Care Patterns Using a Novel Bioinformatics Linkage Strategy.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  4. Improving tuberculosis infection treatment completion among pregnant and postpartum women.Journal of clinical tuberculosis and other mycobacterial diseases · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Adoma ManfulVanderbilt University School of Medicine, Nashville, USA.
Leslie WallerTuberculosis Elimination Program, Metro Public Health Department, Nashville, USA.
Ben KatzTuberculosis Elimination Program, Tennessee Department of Health, Nashville, USA.
Jason CumminsTuberculosis Elimination Program, Tennessee Department of Health, Nashville, USA.
Jon WarkentinTuberculosis Elimination Program, Tennessee Department of Health, Nashville, USA.
Billy ReagonTuberculosis Elimination Program, Metro Public Health Department, Nashville, USA.
Joanna Shaw-KaikaiTuberculosis Elimination Program, Metro Public Health Department, Nashville, USA.
Yuwei ZhuDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, USA.
Yuri F van der HeijdenVanderbilt Tuberculosis Center, Vanderbilt University School of Medicine, Nashville, USA. yuri.vanderheijden@vumc.org.ORCID http://orcid.org/0000-0001-7631-9796
Tennessee Department of Health · USVanderbilt University · USMetro Health Hospital · USVanderbilt University Medical Center · US

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Fluoroquinolone resistance in patients with multidrug-resistant tuberculosisK08AI106420 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI VAN DER HEIJDEN, YURI F. · 2014 to 2018
$848k
National Institutes of Health (US) K08-AI106420NCATS NIH HHS UL1 TR002243NIAID NIH HHS K08 AI106420
6 · The paper itself

Abstract

backgroundTreatment of tuberculosis infection (TBI) in individuals at high risk for tuberculosis (TB) disease is a priority for TB elimination in the US. Newly arrived refugees in Middle Tennessee are screened for TBI, but factors associated with gaps in the TBI care cascade are not well characterized.

methodsWe assessed the TBI care cascade from US entry to completion of treatment for refugees who resettled in Middle Tennessee from 2012 through 2016. We assessed factors associated with treatment initiation and completion using logistic regression models.

resultsOf 6776 refugees who completed initial health screening, 1681 (25%) screened positive for TBI, 1208 were eligible for treatment, 690 started treatment, and 432 completed treatment. Male sex (Odds Ratio [OR]: 1.42; 95% Confidence Interval [CI]: 1.06, 1.89) and screening with interferon gamma release assay compared to tuberculin skin test (OR: 2.89; 95% CI: 1.59, 5.27) were associated with increased treatment initiation; living farther away from TB clinic was associated with decreased treatment initiation (OR: 0.91; 95% CI: 0.83, 0.99). Existing diabetes (OR: 7.27; 95% CI: 1.93, 27.30), receipt of influenza vaccination (OR: 1.65; 95% CI: 1.14, 2.40) and region of origin from South-Eastern or Southern Asia (OR

conclusionsWe determined gaps in the TBI care cascade among refugees in Middle Tennessee. Further assessment of barriers to treatment initiation and completion and interventions to assist refugees are warranted to improve these gaps and prevent TB disease.

Indexed as

AdultAntitubercular AgentsFemaleHealth Services AccessibilityHumansMaleMass ScreeningOdds RatioRefugeesRetrospective StudiesTennesseeTuberculosisYoung AdultAntitubercular AgentsLatent tuberculosisRefugeesTuberculosis infectionTuberculosis prevention

Identifiers

PMID32778060
PMCPMC7418421
OpenAlexW3048811094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.