Evidence map›Paper›PMID 32777969›Full record

Observational studyJournal of the American Heart Association2020

Racial Differences in the Use of Aortic Valve Replacement for Treatment of Symptomatic Severe Aortic Valve Stenosis in the Transcatheter Aortic Valve Replacement Era.

J Matthew Brennan, Martin B Leon, Paige Sheridan, Isabel J Boero, Qinyu Chen, Angela Lowenstern, Vinod Thourani, Sreekanth Vemulapalli, Kevin Thomas, Tracy Y Wang and 1 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Racial disparities in TAVR outcomes in patients with cancer.Frontiers in cardiovascular medicine · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Racial and Ethnic Disparities in Aortic Stenosis.Journal of the American Heart Association · 2022
    Article
  17. Article
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

J Matthew BrennanDuke University School of Medicine Durham NC.
Martin B LeonColumbia University Medical Center and New York Presbyterian Hospital New York NY.
Paige SheridanDepartment of Family Medicine and Public Health University of San Diego San Diego CA.
Isabel J BoeroBoston Consulting Group Boston MA.
Qinyu ChenBoston Consulting Group Boston MA.
Angela LowensternDuke University School of Medicine Durham NC.
Vinod ThouraniGeorgetown University School of MedicineMedstar Heart and Vascular Institute Washington DC.
Sreekanth VemulapalliDuke University School of Medicine Durham NC.
Kevin ThomasDuke University School of Medicine Durham NC.
Tracy Y WangDuke University School of Medicine Durham NC.
Eric D PetersonDuke University School of Medicine Durham NC.
Duke University · USBoston Consulting Group (United States)Boston University · USGeorgetown University · USNewYork–Presbyterian Hospital · US

Funding

Improving the Health of Aging Women and Men.T32AG058529 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LACROIX, ANDREA Z. · 2019 to 2023
$1.2M
NIA NIH HHS T32 AG058529
6 · The paper itself

Abstract

Background Aortic valve replacement (AVR) is a life-saving treatment for patients with symptomatic severe aortic valve stenosis. We sought to determine whether transcatheter AVR has resulted in a more equitable treatment rate by race in the United States. Methods and Results A total of 32 853 patients with symptomatic severe aortic valve stenosis were retrospectively identified via Optum's deidentified electronic health records database (2007-2017). AVR rates in non-Hispanic Black and White patients were assessed in the year after diagnosis. Multivariate Fine-Gray hazards models were used to evaluate the likelihood of AVR by race, with adjustment for patient factors and the managing cardiologist. Time-trend and 1-year symptomatic severe aortic valve stenosis survival analyses were also performed. From 2011 to 2016, the rate of AVR increased from 20.1% to 37.1%. Overall, Black individuals were less likely than Whites to receive AVR (22.9% versus 31.0%; unadjusted hazard ratio [HR], 0.70; 95% CI, 0.62-0.79; fully adjusted HR, 0.76; 95% CI, 0.67-0.85). Yet, during 2015 to 2016, AVR racial differences were attenuated (29.5% versus 35.2%; adjusted HR, 0.86; 95% CI, 0.74-1.02) because of greater uptake of transcatheter AVR in Blacks than Whites (53.4% of AVRs versus 47.3%;

Indexed as

AgedAged, 80 and overAge FactorsAortic Valve StenosisBlack or African AmericanBlack PeopleCardiologistsCause of DeathCohort StudiesComorbidityFemaleHumansIncomeMaleMultivariate AnalysisSurvival Analysisracial differences in caresymptomatic severe aortic valve stenosistranscatheter aortic valve replacement

Identifiers

PMID32777969
PMCPMC7660794
OpenAlexW3048800762

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.