Evidence map›Paper›PMID 32777900›Full record

ReviewTurkish journal of medical sciences2020

IgG4-related disease: a contemporary review

Hazan Karadeniz, Augusto Vaglio

Open access · bronzeAbstract readReview
In one paragraph

Review in Turkish journal of medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
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  13. Frontiers in immunology · 2025
    Article
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  18. A case of type 2 diabetes mellitus complicated with IgG4-related retroperitoneal fibrosis and a literature review.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Review
  19. [Immunoglobulin G4 disease with pancreatic affectation: the mimicker of malignancy].Revista medica del Instituto Mexicano del Seguro Social · 2024
    Article
  20. Immunoglobulin G4-related disease: Multiple organ occupation on CT.JGH open : an open access journal of gastroenterology and hepatology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 3 countries.

Hazan KaradenizDivision of Rheumatology, Departmentof Internal Medicine, Faculty of Medicine, Gazi University, Ankara, TurkeyORCID 0000-0003-4665-3421
Augusto VaglioUniversity of Florence and Meyer Children’s Hospital, Florence, ItalyORCID 0000-0002-3814-9172
Center for Rheumatology · USMeyer Children's Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/aim: Immunoglobulin G4-related disease (IgG4-RD), is an immune-mediated fibroinflammatory condition, which may involve multiple organs and mostly presents with high serum IgG4 levels and specific histopathological characteristics. As IgG4-RD is a relatively new entity the etiology, prevalence and epidemiologic knowledge is quite limited. Although involvement of almost all anatomical regions has been reported, the most commonly affected regions are pancreas, lacrimal glands, salivary glands, retroperitoneum, orbita, lymph nodes, kidney and lungs. Diagnosis is made with combined evaluation of clinical, radiological and histopathological findings. Typical histopathological features include storiform fibrosis, dense lymphoplasmacytic infiltrates and obliterative phlebitis. Its course is typically marked by remission and relapsing attacks and it may lead to fibrosis, destructive lesions in tissues and organ failure unless promptly treated. In the treatment of IgG4-RD, many approaches including surgical resection of tissues, systemic glucocorticoids, steroid-sparing immunosuppressive drugs, and biological agents are employed. Although association is not clear, malignancies are frequently reported in IgG4-RD patients. Therefore, it is prudent to monitor patients for the symptoms of malignant diseases. Conclusion: In this review, recent advances in clinico-pathological characteristics, diagnosis, and treatment of IgG4–RD are discussed.

Indexed as

Immunoglobulin G4-Related DiseaseFemaleGlucocorticoidsHumansImmunosuppressive AgentsMaleGlucocorticoidsImmunosuppressive Agentsclinico-pathological characteristicsdiagnosisIgG4-related diseasetreatment

Identifiers

PMID32777900
PMCPMC7672352
OpenAlexW3049579967

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.