Evidence map›Paper›PMID 32777894›Full record

ArticleAnimal bioscience2021

Single nucleotide polymorphism-based analysis of the genetic structure of Liangshan pig population.

Bin Liu, Linyuan Shen, Zhixian Guo, Mailing Gan, Ying Chen, Runling Yang, Lili Niu, Dongmei Jiang, Zhijun Zhong, Xuewei Li and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animal bioscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Bin LiuCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Linyuan ShenCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Zhixian GuoCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Mailing GanCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Ying ChenSichuan Province General Station of Animal Husbandry, Chengdu 610066, China.
Runling YangAgriculture and Rural Bureau of Mabian Yi Autonomous County, Mabian, 614600, China.
Lili NiuCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Dongmei JiangCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Zhijun ZhongSichuan Academy of Animal Sciences, Chengdu 610066, China.
Xuewei LiCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Shunhua ZhangCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Li ZhuCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan, 611130, China.
Sichuan Agricultural University · CNSichuan Animal Science Academy · CNYanbian University · CN

Funding

National Natural Science Foundation of China 31530073Sichuan Science and Technology Support Program 2016NYZ0050Sichuan Science and Technology Support Program SCSZTD-3-008the earmarked fund for China Agriculture Research System CARS-36-05B
6 · The paper itself

Abstract

objectiveTo conserve and utilize the genetic resources of a traditional Chinese indigenous pig breed, Liangshan pig, we assessed the genetic diversity, genetic structure, and genetic distance in this study.

methodsWe used 50K single nucleotide polymorphism (SNP) chip for SNP detection of 139 individuals in the Liangshan Pig Conservation Farm.

resultsThe genetically closed conserved population consisted of five overlapping generations, and the total effective content of the population (Ne) was 15. The whole population was divided into five boar families and one non-boar family. Among them, the effective size of each generation subpopulation continuously decreased. However, the proportion of polymorphic markers (PN) first decreased and then increased. The average genetic distance of these 139 Liangshan pigs was 0.2823±0.0259, and the average genetic distance of the 14 boars was 0.2723±0.0384. Thus, it can be deduced that the genetic distance changed from generation to generation. In the conserved population, 983 runs of homozygosity (ROH) were detected, and the majority of ROH (80%) were within 100 Mb. The inbreeding coefficient calculated based on ROH showed an average value of 0.026 for the whole population. In addition, the inbreeding coefficient of each generation subpopulation initially increased and then decreased. In the pedigree of the whole conserved population, the error rate of paternal information was more than 11.35% while the maternal information was more than 2.13%.

conclusionThis molecular study of the population genetic structure of Liangshan pig showed loss of genetic diversity during the closed cross-generation reproduction process. It is necessary to improve the mating plan or introduce new outside blood to ensure longterm preservation of Liangshan pig.

Indexed as

Genetic DistanceGenetic DiversityInbreeding CoefficientLiangshan PigSingle Nucleotide Polymorphism (SNP) Chip

Identifiers

PMID32777894
PMCPMC8255872
OpenAlexW3024388236

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.