ArticleCancer research and treatment2021
Chondroblastoma's Lung Metastases Treated with Denosumab in Pediatric Patient.
Article in Cancer research and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Malignant chondroblastoma of the rib with scalp metastases in an adult patient: case report with molecular characterization.Virchows Archiv : an international journal of pathology · 2026Article
- Article
- Percutaneous Management of Benign Bone Cysts and Tumors in Children.Seminars in interventional radiology · 2025Review
- Clinical characteristics and outcomes of patients with chondroblastoma undergoing surgery with various adjuvant procedures: a retrospective study of 59 cases.BMC surgery · 2025Article
- Comprehensive Insights into Chondroblastoma Metastasis: Metastatic Patterns and Therapeutic Approaches.Cancers · 2024Review
- Efficacy of denosumab treatment for lung metastasis secondary to proximal humerus chondroblastoma.Saudi medical journal · 2024Article
- 3D Specimen Scanning and Mapping in Musculoskeletal Oncology: A Feasibility Study.Annals of surgical oncology · 2024Article
- Benign tumors of the chest wall.Journal of thoracic disease · 2024Review
- Article
- Pulmonary Metastases of Chondroblastoma in a Pediatric Patient: A Case Report and Review of Literature.Cureus · 2022Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chondroblastoma is a rare benign chondrogenic tumor that occurs in skeletally immature patients between ages 10 and 20 years old. In literature are reported few cases of lung metastases, mainly occurred after surgery or local recurrences. There is no evidence on the pathogenesis of lung metastasis, as well as pulmonary disease course. Few treatments for metastases with aggressive behavior were based on chemotherapy regimen employed in other sarcoma with no results or not satisfying ones. Denosumab is approved for treatment of giant cell tumors and it is under investigation for other giant cell-rich bone tumors. Here, we report a case of a 16-year-old male chondroblastoma of the left humerus with bilateral lung metastases at presentation and progressing during follow-up, treated with denosumab for almost 2 years. We confirm that denosumab treatment can be effective in controlling chondroblastoma metastasis and it has been a safe procedure in an adolescent patient.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.