ArticlePsychiatry research2020
Circadian rhythm in negative affect: Implications for mood disorders.
Article in Psychiatry research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05616819 (Regulating Mood and Suicidal Ideation With Morning Light Exposure Treatment), which is not on this map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Regulating Mood and Suicidal Ideation With Morning Light Exposure Treatment
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- A Systematic Review on Insomnia and Circadian Rhythms Desynchronization in Obsessive-Compulsive Disorder: From Childhood to Adulthood.Journal of sleep research · 2026Pooled it
- Biological rhythms in premenstrual syndrome and premenstrual dysphoric disorder: a systematic review.BMC women's health · 2024Pooled it
- Nocturnal Risk Assessment and Its Association With Anxiety Symptoms.Psychophysiology · 2026Trial
- Large-scale patterns of self-reported mood and sleep across the day and week on an online cognitive-training platform.PLOS digital health · 2026Article
- Sleeping Less Than Usual Is Associated With Greater Daily Depression and Higher Reactivity to Negative Interpersonal Events Among Suicidal Adolescents.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2026Article
- Circadian Timing Moderates Diurnal Positive Affect Rhythms in Adolescents.Journal of biological rhythms · 2026Article
- Melatonin Circadian Phase Timing and Stability: Associations With Mood Symptoms Among a Clinically-Enriched Sample of Young Adults With Mood Disorders.Journal of pineal research · 2026Article
- Understanding Latine disparities in nocturnal wakefulness as a suicide risk factor.Sleep epidemiology · 2025Article
- Different Protocols of Circadian Rhythm Disruptions Differentially Affect Locomotor Activity, and Anxiety- and Compulsive-Like Behaviors in Male vs. Female Wistar Rats along with the Significant Involvement of GSK-3β in Females.Molecular neurobiology · 2025Article
- Online Social Networking as a Social Zeitgeber.Current psychiatry reports · 2025Review
- Adverse childhood experiences and chronic pain in adolescent patients with depressive disorder: the mediating role of circadian rhythm disruption.BMC psychiatry · 2025Article
- The Temporal Dynamics of Sleep Disturbances, Depression, and Self-Injurious Thoughts and Behaviors in Preadolescents: A Year-Long Intensive Longitudinal Study.Research on child and adolescent psychopathology · 2025Article
- Network Analysis of Fear of Recurrence and Sleep Disorders in Ovarian Cancer Patients Undergoing Chemotherapy.International journal of women's health · 2025Article
- [Effects of Extreme Environments on Human Sleep].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024Review
- Risk for Suicide and Homicide Peaks at Night: Findings From the National Violent Death Reporting System, 35 States, 2003-2017.The Journal of clinical psychiatry · 2024Article
- Waking up on the wrong side of the bed: Depression severity moderates daily associations between sleep duration and morning affect.Journal of sleep research · 2024Article
- Mood correlates with circadian alignment in healthy individuals.Sleep health · 2024Article
- Chronotype and Affective Response to Sleep Restriction and Subsequent Sleep Deprivation.Journal of biological rhythms · 2024Article
- Obesity alters the circadian profiles of energy metabolism and glucose regulation in humans.Obesity (Silver Spring, Md.) · 2024Article
- Unraveling the interplay of circadian rhythm and sleep deprivation on mood: A Real-World Study on first-year physicians.PLOS digital health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
In humans, there is an endogenous, near 24-h (i.e., circadian) variation in mood with the best mood occurring during the circadian day and the worst mood occurring during the circadian night. Only positive affect, and not negative affect, has been shown to contribute to this circadian rhythm. We discovered a sharp circadian peak in negative affect during the circadian night coincident with a circadian trough in positive affect. These findings may help explain the association of depression with insomnia, the increased risk of suicide with nocturnal wakefulness, and the correlation between circadian misalignment and symptom severity in Major Depressive Disorder.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.