ArticleThe clinical respiratory journal2020
Metabolic syndrome prevalence in patients with obstructive sleep apnea syndrome and chronic obstructive pulmonary disease: Relationship with systemic inflammation.
Article in The clinical respiratory journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Pooled it
- Metabolic syndrome and incident thyroid cancer risk in adults: A systematic review and meta-analysis.Biomolecules & biomedicine · 2026Pooled it
- Precision Medicine in Overlap Syndrome (COPD-Obstructive Sleep Apnea): From Phenotypes and Endotypes to Treatable Traits.Advances in respiratory medicine · 2026Review
- 2-Methoxyestradiol attenuates lung injury induced by chronic intermittent hypoxia via inhibiting the HIF1-α/SLC7A11 pathway.Scientific reports · 2025Article
- Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnea Coexistence: From Pathophysiology to Clinical Complications.International journal of chronic obstructive pulmonary disease · 2025Review
- Assessment of Metabolic Syndrome in Patients with Chronic Obstructive Pulmonary Disease: A 6-Month Follow-Up Study.Diagnostics (Basel, Switzerland) · 2024Article
- The Impact of Lung Function on Sleep Monitoring in Obstructive Sleep Apnea Associated with Obstructive Lung Diseases: Insights from a Clinical Study.Journal of clinical medicine · 2024Article
- Multimorbidities in COPD are Associated With Increased Exacerbations and Health Care Resource Utilization in Real-World Patients from a U.S. Database.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2024Article
- Prevalence and Characteristics of Patients with Obstructive Sleep Apnea and Chronic Obstructive Pulmonary Disease: Overlap Syndrome.Life (Basel, Switzerland) · 2024Article
- Functional capacity and inflammatory biomarkers as predictors for right atrial volume index in COPD patients.The international journal of cardiovascular imaging · 2023Article
- Correlation of White Blood Cell, Neutrophils, and Hemoglobin with Metabolic Syndrome and Its Components.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- The prevalence and clustering of metabolic syndrome risk components in Chinese population: a cross-sectional study.Frontiers in endocrinology · 2023Article
- The Overlap Syndrome of Obstructive Sleep Apnea and Chronic Obstructive Pulmonary Disease: A Systematic Review.Biomedicines · 2022Review
- MAFLD associated with COPD via systemic inflammation independent of aging and smoking in men.Diabetology & metabolic syndrome · 2022Article
- High-Density Lipoproteins: A Role in Inflammation in COPD.International journal of molecular sciences · 2022Review
- Prevalence and Influencing Factors of Metabolic Syndrome among Adults in China from 2015 to 2017.Nutrients · 2021Article
- Towards Validating the Effectiveness of Obstructive Sleep Apnea Classification from Electronic Health Records Using Machine Learning.Healthcare (Basel, Switzerland) · 2021Article
- A review of therapies for the overlap syndrome of obstructive sleep apnea and chronic obstructive pulmonary disease.FASEB bioAdvances · 2021Article
- Does Modern Lifestyle Favor Neuroimmunometabolic Changes? A Path to Obesity.Frontiers in nutrition · 2021Review
- Metabolic syndrome prevalence in patients with obstructive sleep apnea syndrome and chronic obstructive pulmonary disease: Relationship with systemic inflammation.The clinical respiratory journal · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
objectivesMetabolic syndrome (MetS) is frequent in both chronic obstructive pulmonary disease (COPD) and Obstructive sleep apnea (OSA). The aim of this study was to assess the frequency of MetS and the status of systemic inflammation in overlap syndrome.
methodsA total of 151 consecutive COPD patients were recruited in this cross-sectional study. Spirometry and polysomnography were done in all patients. The MetS was defined according to the criteria of the International Diabetes Federation. Anthropometry, metabolic parameters and inflammatory biomarkers: IL-6, TNF-α, leptin, resistin and adiponectin were recorded.
resultsOSA was present in 19.2% COPD patients. Subjects with overlap syndrome had higher neck and waist circumference compared to those with COPD alone. Significant differences in levels of blood pressure, lipid metabolic and glucose metabolic were found between two groups with overlap and COPD, as well as inflammatory biomarkers. Prevalence of MetS was increased in overlap group. Multivariate logistic regression showed that BMI, systolic BP when fall asleep and recumbent angiotens levels as significant independent predictors of the presence of Mets in overlap syndrome.
conclusionThis study shows that MetS is frequent in patients with overlap. Overlap syndrome indicates a higher cardiometabolic risk and higher levels of systemic inflammatory.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.