Evidence map›Paper›PMID 32777083›Full record

Trial reportAmerican journal of hematology2020

Reduction in transcranial doppler ultrasound (TCD) velocity after regular blood transfusion therapy is associated with a change in hemoglobin S fraction in sickle cell anemia.

Lori C Jordan, Mark Rodeghier, Manus J Donahue, Michael R DeBaun

Abstract readLetterRandomized Controlled Trial
In one paragraph

Trial report in American journal of hematology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lori C JordanDivision of Pediatric Neurology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee.ORCID 0000-0001-7240-0415
Mark RodeghierRodeghier Consultants, Chicago, Illinois.
Manus J DonahueDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee.ORCID 0000-0002-4123-9275
Michael R DeBaunVanderbilt-Meharry Sickle Cell Center for Excellence, Vanderbilt University Medical Center, Nashville, Tennessee.ORCID 0000-0002-0574-1604

Funding

Silent Cerebral Infarct Multi-Center Clinical TrialU01NS042804 · NINDS · WASHINGTON UNIVERSITY · PI DEBAUN, MICHAEL R. · 2003 to 2010
$20.7M
Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lea K Davis · 2020 to 2026
$10.3M
MRI-based quantitative brain oxygen metabolism identifying high risk of infarct recurrence in sickle cell anemiaR01NS096127 · NINDS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI JORDAN, LORI CHAFFIN · 2016 to 2020
$1.7M
Mentoring in Patient-Oriented Research focused on Neurological Complications of Sickle Cell DiseaseK24HL147017 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI JORDAN, LORI CHAFFIN · 2019 to 2023
$547k
NHLBI NIH HHS K24 HL147017NICHD NIH HHS P50 HD103537NINDS NIH HHS R01 NS096127NINDS NIH HHS U01 NS042804
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anemia, Sickle CellBlood TransfusionBrainHemoglobin, SickleUltrasonography, Doppler, TranscranialAdolescentBlood Flow VelocityChildChild, PreschoolFemaleHumansMaleHemoglobin, Sickle

Identifiers

PMID32777083
PMCPMC7727928

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.