Trial reportRadiology2021
Diagnostic Performance of Chest CT for SARS-CoV-2 Infection in Individuals with or without COVID-19 Symptoms.
Trial report in Radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 106 citations in OpenAlex.
- Diagnostic performance of CO-RADS for COVID-19: a systematic review and meta-analysis.European radiology · 2022Pooled it
- Diagnostic value of chest computed tomography imaging for COVID-19 based on reverse transcription-polymerase chain reaction: a meta-analysis.Infectious diseases of poverty · 2021Pooled it
- Coronary artery calcification is associated with reduced survival in mechanically ventilated COVID-19 patients in the MaastrICCht cohort.Scientific reports · 2026Article
- AI-derived CT biomarker score for robust COVID-19 mortality prediction across multiple waves and regions using machine learning.Scientific reports · 2025Article
- The current state of forensic imaging - post mortem imaging.International journal of legal medicine · 2025Review
- Nanomaterial-Based Biosensors for the Detection of COVID-19.Indian journal of microbiology · 2025Article
- Diagnostic performance of standardized typical CT findings for COVID-19: a systematic review and meta-analysis.Insights into imaging · 2023Article
- Novel Corona Virus 2019 Disease: Assessment on High-Resolution Computed Tomography Thorax.Cureus · 2023Article
- Chest computed tomography of suspected COVID-19 pneumonia in the Emergency Department: comparative analysis between patients with different vaccination status.Polish journal of radiology · 2023Article
- Artificial intelligence for reducing the radiation burden of medical imaging for the diagnosis of coronavirus disease.European physical journal plus · 2023Review
- Clinical Characteristics and Management of Patients with a Suspected COVID-19 Infection in Emergency Departments: A European Retrospective Multicenter Study.Journal of personalized medicine · 2022Article
- Imaging strategies used in emergency departments for the diagnostic workup of COVID-19 patients during the first wave of the pandemic: a cost-effectiveness analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022Article
- Characteristics and clinical outcomes of SARS-CoV-2 infection in adult patients with acute leukemia in France.Leukemia research · 2022Article
- An Entropy-Based Measure of Complexity: An Application in Lung-Damage.Entropy (Basel, Switzerland) · 2022Article
- Review
- Impact of X-radiation in the management of COVID-19 disease.World journal of radiology · 2022Review
- Evaluation of Patients Treated in Intensıve Care Due to COVID-19: A Retrospective Study.Infection & chemotherapy · 2022Article
- Diagnostic accuracy of CO-RADS in patients with suspected Coronavirus Disease-2019: A single center experience.Clinical imaging · 2022Article
- Diagnostic Performance of Antigen Rapid Diagnostic Tests, Chest Computed Tomography, and Lung Point-of-Care-Ultrasonography for SARS-CoV-2 Compared with RT-PCR Testing: A Systematic Review and Network Meta-Analysis.Diagnostics (Basel, Switzerland) · 2022Review
- Prevention and Treatment of Life-Threatening COVID-19 May Be Possible with Oxygen Treatment.Life (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background The use of chest CT for coronavirus disease 2019 (COVID-19) diagnosis or triage in health care settings with limited severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) capacity is controversial. COVID-19 Reporting and Data System (CO-RADS) categorization of the level of COVID-19 suspicion might improve diagnostic performance. Purpose To investigate the value of chest CT with CO-RADS classification to screen for asymptomatic SARS-CoV-2 infections and to determine its diagnostic performance in individuals with COVID-19 symptoms during the exponential phase of viral spread. Materials and Methods In this secondary analysis of a prospective trial, from March 2020 to April 2020, parallel SARS-CoV-2 PCR and CT with categorization of COVID-19 suspicion was performed with CO-RADS for individuals with COVID-19 symptoms and control participants without COVID-19 symptoms admitted to the hospital for medical emergencies unrelated to COVID-19. CT with CO-RADS was categorized on a five-point scale from 1 (very low suspicion) to 5 (very high suspicion). Area under the receiver operating curve (AUC) was calculated in symptomatic versus asymptomatic individuals to predict positive SARS-CoV-2 PCR, and likelihood ratios for each CO-RADS score were used for rational selection of diagnostic thresholds. Results A total of 859 individuals (median age, 70 years; interquartile range, 52-81 years; 443 men) with COVID-19 symptoms and 1138 control participants (median age, 68 years; interquartile range, 52-81 years; 588 men) were evaluated. CT with CO-RADS had good diagnostic performance (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.