ArticleAmerican journal of physiology. Endocrinology and metabolism2020
Testosterone supplementation upregulates androgen receptor expression and translational capacity during severe energy deficit.
Article in American journal of physiology. Endocrinology and metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The trial behind it
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Effects of testosterone enanthate on aggression, risk-taking, competition, mood, and other cognitive domains during 28 days of severe energy deprivation.Psychopharmacology · 2024Trial
- Bioelectrical impedance phase angle is associated with physical performance before but not after simulated multi-stressor military operations.Physiological reports · 2023Trial
- Metabolomics of testosterone enanthate administration during severe-energy deficit.Metabolomics : Official journal of the Metabolomic Society · 2022Trial
- Molecular Regulators of Muscle Mass and Mitochondrial Remodeling Are Not Influenced by Testosterone Administration in Young Women.Frontiers in endocrinology · 2022Trial
- Endocrine dynamics of special operations forces across mission cycles: implications for human stress physiology.European journal of applied physiology · 2026Article
- Computational modeling identifies protective mechanisms of estrogen and testosterone against atrial fibrosis.American journal of physiology. Heart and circulatory physiology · 2026Article
- Bioavailable testosterone and androgen receptor activation, but not total testosterone, are associated with muscle mass and strength in females.The Journal of physiology · 2025Article
- Comparative analysis of circulating metabolomic profiles identifies shared metabolic alterations across distinct multistressor military training exercises.Physiological genomics · 2024Article
- Morin hydrate ameliorates heat-induced testicular impairment in a mouse model.Molecular biology reports · 2024Article
- From mitochondria to sarcopenia: role of 17β-estradiol and testosterone.Frontiers in endocrinology · 2023Review
- A systemic study on the vulnerability and fatality of prostate cancer patients towards COVID-19 through analysis of the TMPRSS2, CXCL10 and their co-expressed genes.Genomics & informatics · 2022Article
- Testosterone undecanoate administration prevents declines in fat-free mass but not physical performance during simulated multi-stressor military operations.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Lean mass sparing in resistance-trained athletes during caloric restriction: the role of resistance training volume.European journal of applied physiology · 2022Review
- Exposure to sevoflurane results in changes of transcription factor occupancy in sperm and inheritance of autism†.Biology of reproduction · 2021Article
- Effects of testosterone undecanoate on performance during multi-stressor military operations: A trial protocol for the Optimizing Performance for Soldiers II study.Contemporary clinical trials communications · 2021Article
Corrections and comments
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Authors and funding
14 authors at 6 institutions in 1 country.
Funding
Abstract
Testosterone supplementation during energy deficit promotes whole body lean mass accretion, but the mechanisms underlying that effect remain unclear. To elucidate those mechanisms, skeletal muscle molecular adaptations were assessed from muscle biopsies collected before, 1 h, and 6 h after exercise and a mixed meal (40 g protein, 1 h postexercise) following 14 days of weight maintenance (WM) and 28 days of an exercise- and diet-induced 55% energy deficit (ED) in 50 physically active nonobese men treated with 200 mg testosterone enanthate/wk (TEST) or placebo (PLA) during the ED. Participants (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.