Evidence map›Paper›PMID 32776556›Full record

ArticleJournal of medical virology2021

Elevated MUC1 and MUC5AC mucin protein levels in airway mucus of critical ill COVID-19 patients.

Wenju Lu, Xiaoqing Liu, Tao Wang, Fei Liu, Airu Zhu, Yongping Lin, Jieping Luo, Feng Ye, Jianxing He, Jincun Zhao and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of medical virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 3 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 3 syntheses or guidelines pooled it, 110 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Mucins and Respiratory Virus Infection.Annual review of virology · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Observational
  10. Review
  11. Impact of Nebulized BromAcLife (Basel, Switzerland) · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Deciphering the Relationship between SARS-CoV-2 and Cancer.International journal of molecular sciences · 2023
    Review
  18. Review
  19. Article
  20. Prevalence and Mechanisms of Mucus Accumulation in COVID-19 Lung Disease.American journal of respiratory and critical care medicine · 2022
    Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Wenju LuDivision of Respiratory Medicine, State Key Laboratory of Respiratory Diseases, Guangdong Key Laboratory of Vascular Diseases, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Health, Guangzhou, Guangdong, China.
Xiaoqing LiuDivision of Respiratory Medicine, State Key Laboratory of Respiratory Diseases, Guangdong Key Laboratory of Vascular Diseases, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Health, Guangzhou, Guangdong, China.
Tao WangDivision of Respiratory Medicine, State Key Laboratory of Respiratory Diseases, Guangdong Key Laboratory of Vascular Diseases, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Health, Guangzhou, Guangdong, China.
Fei LiuDivision of Respiratory Medicine, State Key Laboratory of Respiratory Diseases, Guangdong Key Laboratory of Vascular Diseases, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Health, Guangzhou, Guangdong, China.
Airu ZhuDivision of Respiratory Medicine, State Key Laboratory of Respiratory Diseases, Guangdong Key Laboratory of Vascular Diseases, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Health, Guangzhou, Guangdong, China.
Yongping LinDivision of Respiratory Medicine, State Key Laboratory of Respiratory Diseases, Guangdong Key Laboratory of Vascular Diseases, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Health, Guangzhou, Guangdong, China.
Jieping Luo
Feng YeDivision of Respiratory Medicine, State Key Laboratory of Respiratory Diseases, Guangdong Key Laboratory of Vascular Diseases, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Health, Guangzhou, Guangdong, China.
Jianxing HeDivision of Respiratory Medicine, State Key Laboratory of Respiratory Diseases, Guangdong Key Laboratory of Vascular Diseases, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Health, Guangzhou, Guangdong, China.
Jincun ZhaoDivision of Respiratory Medicine, State Key Laboratory of Respiratory Diseases, Guangdong Key Laboratory of Vascular Diseases, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Health, Guangzhou, Guangdong, China.
Yiming LiDivision of Respiratory Medicine, State Key Laboratory of Respiratory Diseases, Guangdong Key Laboratory of Vascular Diseases, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Health, Guangzhou, Guangdong, China.
Nanshan ZhongDepartment of Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
State Key Laboratory of Respiratory Disease · CNGuangzhou Medical University · CNFirst Affiliated Hospital of Guangzhou Medical University · CN

Funding

National Key R&D Project 2016YFC0903700 and 2016YFC1304102National Natural Science Foundation of China 81520108001National Natural Science Foundation of China 81770043
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cohort StudiesCOVID-19Critical IllnessFemaleHumansMaleMiddle AgedMucin-1Mucin 5ACMucusRespiratory SystemMUC1 protein, humanMUC5AC protein, humanMucin-1Mucin 5ACcoronavirusprotein extractionsystemic immunity

Identifiers

PMID32776556
PMCPMC7436726
OpenAlexW3047978274

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.