Evidence map›Paper›PMID 32776316›Full record

ArticleHerz2021

A simple formula to predict echocardiographic diastolic dysfunction-electrocardiographic diastolic index.

Mert İlker Hayıroğlu, Tufan Çınar, Vedat Çiçek, Süha Asal, Şahhan Kılıç, Nurgül Keser, Mehmet Uzun, Ahmet Lütfullah Orhan

Abstract read
PubMed Publisher
In one paragraph

Article in Herz, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mert İlker HayıroğluDepartment of Cardiology, Haydarpasa Sultan Abdulhamid Han Training and Research Hospital, 34668, Kadikoy-Istanbul, Turkey. mertilkerh@yahoo.com.
Tufan ÇınarDepartment of Cardiology, Haydarpasa Sultan Abdulhamid Han Training and Research Hospital, 34668, Kadikoy-Istanbul, Turkey.
Vedat ÇiçekDepartment of Cardiology, Haydarpasa Sultan Abdulhamid Han Training and Research Hospital, 34668, Kadikoy-Istanbul, Turkey.
Süha AsalDepartment of Cardiology, Haydarpasa Sultan Abdulhamid Han Training and Research Hospital, 34668, Kadikoy-Istanbul, Turkey.
Şahhan KılıçDepartment of Cardiology, Haydarpasa Sultan Abdulhamid Han Training and Research Hospital, 34668, Kadikoy-Istanbul, Turkey.
Nurgül KeserDepartment of Cardiology, Haydarpasa Sultan Abdulhamid Han Training and Research Hospital, 34668, Kadikoy-Istanbul, Turkey.
Mehmet UzunDepartment of Cardiology, Haydarpasa Sultan Abdulhamid Han Training and Research Hospital, 34668, Kadikoy-Istanbul, Turkey.
Ahmet Lütfullah OrhanDepartment of Cardiology, Haydarpasa Sultan Abdulhamid Han Training and Research Hospital, 34668, Kadikoy-Istanbul, Turkey.
Haydarpaşa Numune Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiastolic dysfunction (DD) in transthoracic echocardiography (TTE), which is a poorly understood entity due to its limited treatment, is frequently encountered in daily clinical practice of cardiology. An electrocardiographic (ECG) index to predict echocardiographic DD has not been elucidated yet. We aim to exhibit an electrocardiographic diastolic index (EDI) to predict TTE DD with high sensitivity and specificity. MATERIALS AND

methodsIn this retrospective investigation, we tested the DD predictive value of EDI [aVL R amplitude × (V1S amplitude + V5R amplitude)/D1 P amplitude] on 204 consecutive adult patients without known coronary artery disease. Patients were divided into tertiles according to their EDI starting from the lowest one. The power of the EDI was also compared with the subunits of its formula by a receiver operating curve (ROC) analysis.

resultsAfter adjustment for confounding baseline variables, EDI in tertile 3 was associated with 24.2-fold hazard ratio of DD (odds ratio 25.2, 95% confidence interval [CI] 11.2-51.1, p < 0.001). The Spearman correlation analysis revealed moderate correlation between E/e' and EDI. A ROC analysis showed that the optimal cut-off value of the EDI to predict DD was 8.53 mV with 70% sensitivity and 70% specificity (area under the curve 0.78; 95% CI 0.71-0.84; p < 0.001).

conclusionThe electrocardiographic diastolic index (EDI), which is an inexpensive, feasible, and easy to use formula, appears to have a considerable role to predict diastolic dysfunction (DD) in adult patients.

Indexed as

Ventricular Dysfunction, LeftAdultDiastoleEchocardiographyElectrocardiographyHumansRetrospective StudiesAtrial fibrillationElectrocardiographyHeart diseasesP waveR wave

Identifiers

PMID32776316
OpenAlexW3048867135

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.