ArticleWorld journal of urology2021
Timing and delay of radical prostatectomy do not lead to adverse oncologic outcomes: results from a large European cohort at the times of COVID-19 pandemic.
Article in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Oncologic impact of delaying radical prostatectomy in men with intermediate- and high-risk prostate cancer: a systematic review.World journal of urology · 2021Pooled it
- Impact of Biopsy-to-Radical Prostatectomy Interval on Adverse Pathological Outcomes in High-Risk Localized and Locally Advanced Prostate Cancer.Diagnostics (Basel, Switzerland) · 2026Article
- The COVID-19 pandemic and Urology - reflecting on successful initiatives and lessons in Australia.BJU international · 2025Review
- Impact of the COVID-19 Prioritization Recommendations on Pathological Stages of Urologic Malignancies: A Real-World Analysis at a High-Volume Referral Institution.Journal of clinical medicine · 2024Article
- The impact of delayed diagnosis and treatment due to COVID-19 on Australian thyroid cancer patients: a qualitative interview study.BMJ open · 2024Article
- Delays in diagnosis and surgery of sarcoma patients during the COVID-19 outbreak in Spain.Therapeutic advances in medical oncology · 2024Article
- Article
- The Impact of Covid-19 Pandemic on Genitourinary Cancers Stage and Grade.Clinical genitourinary cancer · 2023Article
- The impact of coronavirus disease 2019 (COVID-19) pandemic on urologic cancer care: did we throw the baby out with the bathwater?Translational andrology and urology · 2023Article
- Impact of COVID-19 on Uro-Oncological Patients: A Comprehensive Review of the Literature.Microorganisms · 2023Review
- Increasing surgical wait time does not increase the risk of node positive prostate cancer: Implications for surgical planning during the COVID-19 pandemic and beyond.Frontiers in urology · 2023Article
- Can We Identify Patients in Danger of Delayed Treatment? Management of COVID-19 Pandemic Backlog in Urology Care in Poland.International journal of environmental research and public health · 2022Article
- Suitability of conventional systematic vs. MRI-guided targeted biopsy approaches to assess surgical treatment delay for radical prostatectomy.World journal of urology · 2022Article
- How has the COVID-19 pandemic influenced prostate cancer?-a tertiary single-centre analysis of oncological results, diagnosis and treatment times.Translational andrology and urology · 2022Article
- The continuing impacts of the COVID-19 pandemic on diagnosis and surgical prostate cancer management: a population-based analysis.ANZ journal of surgery · 2022Article
- The Impact of the Ongoing COVID-19 Epidemic on the Increasing Risk of Adverse Pathology in Prostate Cancer Patients Undergoing Radical Prostatectomy.Current oncology (Toronto, Ont.) · 2022Article
- COVID-19 pandemic impact on uro-oncological disease outcomes at an Italian tertiary referral center.World journal of urology · 2022Article
- Perioperative outcomes of patients undergoing urological elective surgery during the COVID-19 pandemic: a national overview across 28 Italian institutions.Central European journal of urology · 2021Article
- Impact of COVID-19 pandemic on prostate cancer outcomes at an uro-oncology referral center.International braz j urol : official journal of the Brazilian Society of UrologyArticle
- Changes in Surgical Admissions and Outcomes During and After the COVID-19 Pandemic: An Exploration of the Australian and New Zealand Audit of Surgical Mortality (ANZASM).ANZ journal of surgeryArticle
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe current COVID-19 pandemic is transforming our urologic practice and most urologic societies recommend to defer any surgical treatment for prostate cancer (PCa) patients. It is unclear whether a delay between diagnosis and surgical management (i.e., surgical delay) may have a detrimental effect on oncologic outcomes of PCa patients. The aim of the study was to assess the impact of surgical delay on oncologic outcomes.
methodsData of 926 men undergoing radical prostatectomy across Europe for intermediate and high-risk PCa according to EAU classification were identified. Multivariable analysis using binary logistic regression and Cox proportional hazard model tested association between surgical delay and upgrading on final pathology, lymph-node invasion (LNI), pathological locally advanced disease (pT3-4 and/or pN1), need for adjuvant therapy, and biochemical recurrence. Kaplan-Meier analysis was used to estimate BCR-free survival after surgery as a function of surgical delay using a 3 month cut-off.
resultsMedian follow-up and surgical delay were 26 months (IQR 10-40) and 3 months (IQR 2-5), respectively. We did not find any significant association between surgical delay and oncologic outcomes when adjusted to pre- and post-operative variables. The lack of such association was observed across EAU risk categories.
conclusionDelay of several months did not appear to adversely impact oncologic results for intermediate and high-risk PCa, and support an attitude of deferring surgery in line with the current recommendation of urologic societies.
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