Evidence map›Paper›PMID 32776208›Full record

ArticleMedical & biological engineering & computing2020

Differential diagnosis of asthma and restrictive respiratory diseases by combining forced oscillation measurements, machine learning and neuro-fuzzy classifiers.

Jorge L M Amaral, Alexandre G Sancho, Alvaro C D Faria, Agnaldo J Lopes, Pedro L Melo

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Article in Medical & biological engineering & computing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jorge L M AmaralDepartment of Electronics and Telecommunications Engineering, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
Alexandre G SanchoBiomedical Instrumentation Laboratory, Institute of Biology Roberto Alcantara Gomes and Laboratory of Clinical and Experimental Research in Vascular Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
Alvaro C D FariaBiomedical Instrumentation Laboratory, Institute of Biology Roberto Alcantara Gomes and Laboratory of Clinical and Experimental Research in Vascular Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
Agnaldo J LopesPulmonary Function Laboratory, Pedro Ernesto University Hospital, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
Pedro L MeloBiomedical Instrumentation Laboratory, Institute of Biology Roberto Alcantara Gomes and Laboratory of Clinical and Experimental Research in Vascular Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil. plopes@uerj.br.ORCID http://orcid.org/0000-0002-2081-6619
Universidade do Estado do Rio de Janeiro · BRHospital Universitário Pedro Ernesto · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To design machine learning classifiers to facilitate the clinical use and increase the accuracy of the forced oscillation technique (FOT) in the differential diagnosis of patients with asthma and restrictive respiratory diseases. FOT and spirometric exams were performed in 97 individuals, including controls (n = 20), asthmatic patients (n = 38), and restrictive (n = 39) patients. The first experiment of this study showed that the best FOT parameter was the resonance frequency, providing moderate accuracy (AUC = 0.87). In the second experiment, a neuro-fuzzy classifier and different supervised machine learning techniques were investigated, including k-nearest neighbors, random forests, AdaBoost with decision trees, and support vector machines with a radial basis kernel. All classifiers achieved high accuracy (AUC ≥ 0.9) in the differentiation between patient groups. In the third and fourth experiments, the use of different feature selection techniques allowed us to achieve high accuracy with only three FOT parameters. In addition, the neuro-fuzzy classifier also provided rules to explain the classification. Neuro-fuzzy and machine learning classifiers can aid in the differential diagnosis of patients with asthma and restrictive respiratory diseases. They can assist clinicians as a support system providing accurate diagnostic options.

Indexed as

AdultAgedAlgorithmsArea Under CurveAsthmaCase-Control StudiesDiagnosis, Computer-AssistedDiagnosis, DifferentialFemaleFuzzy LogicHumansMachine LearningMaleMiddle AgedRespiratory Tract DiseasesSpirometryClinical decision support systemDiagnostic of respiratory diseasesDifferential diagnosisForced oscillation techniqueRespiratory oscillometry

Identifiers

PMID32776208
OpenAlexW3047858667

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.