ArticleJournal of endocrinological investigation2021
Impact of diabetes on COVID-19-related in-hospital mortality: a retrospective study from Northern Italy.
Article in Journal of endocrinological investigation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 8 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 8 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Prognostic factors for mortality, intensive care unit and hospital admission due to SARS-CoV-2: a systematic review and meta-analysis of cohort studies in Europe.European respiratory review : an official journal of the European Respiratory Society · 2022Pooled it
- Association of serum C-reactive protein (CRP) and D-dimer concentration on the severity of COVID-19 cases with or without diabetes: a systematic review and meta-analysis.Expert review of endocrinology & metabolism · 2022Pooled it
- The isolated effect of age on the risk of COVID-19 severe outcomes: a systematic review with meta-analysis.BMJ global health · 2021Pooled it
- Pooled it
- The effect of cardiovascular disease and acute cardiac injury on fatal COVID-19: a meta-analysis.The American journal of emergency medicine · 2021Pooled it
- Pre-existing health conditions and severe COVID-19 outcomes: an umbrella review approach and meta-analysis of global evidence.BMC medicine · 2021Pooled it
- Pooled it
- The potential association between common comorbidities and severity and mortality of coronavirus disease 2019: A pooled analysis.Clinical cardiology · 2020Pooled it
- SARS-CoV-2 infection and two-year longitudinal clinical trajectory in pulmonary hypertension: a single-center retrospective exploratory cohort study.Frontiers in public health · 2026Article
- Observational
- Predictors of mortality and ICU requirement in hospitalized COVID-19 patients with diabetes: A multicentre study.Nursing open · 2023Article
- Association of government effectiveness, logistics performance, IT systems and income with COVID-19 mortality.Heliyon · 2023Article
- Clinical and laboratory profile and outcomes of hospitalized COVID-19 patients with type 2 diabetes mellitus in Ghana - A single-center study.Endocrinology, diabetes & metabolism · 2023Article
- A deep transfer learning approach for COVID-19 detection and exploring a sense of belonging with Diabetes.Frontiers in public health · 2023Article
- Interpretable Machine Learning for Inpatient COVID-19 Mortality Risk Assessments: Diabetes Mellitus Exclusive Interplay.Sensors (Basel, Switzerland) · 2022Article
- Concordance between indirect fibrosis and steatosis indices and their predictors in subjects with overweight/obesity.Eating and weight disorders : EWD · 2022Article
- J-shaped associations and joint effects of fasting glucose with inflammation and cytokines on COVID-19 mortality.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022Article
- Post-acute cardiac complications following SARS-CoV-2 infection in partial lipodystrophy due to LMNA gene p.R349W mutation.Journal of endocrinological investigation · 2022Article
- Factors associated with mortality in hospitalized cardiovascular disease patients infected with COVID-19.Immunity, inflammation and disease · 2022Article
- Glucose control in home-isolated adults with type 1 diabetes affected by COVID-19 using continuous glucose monitoring.Journal of endocrinological investigation · 2022Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to evaluate the impact of pre-existing diabetes on in-hospital mortality in patients admitted for Coronavirus Disease 2019 (COVID-19).
methodsThis is a single center, retrospective study conducted at Policlinico di Monza hospital, located in the Lombardy region, Northern Italy. We reviewed medical records of 373 consecutive adult patients who were hospitalized with COVID-19 between February 22 and May 15, 2020. Data were collected on diabetes status, comorbid conditions and laboratory findings. Multivariable logistic regression was performed to evaluate the effect of diabetes on in-hospital mortality after adjustment for potential confounding variables.
resultsMean age of the patients was 72 ± 14 years (range 17-98), 244 (65.4%) were male and 69 (18.5%) had diabetes. The most common comorbid conditions were hypertension (237 [64.8%]), cardiovascular disease (140 [37.7%]) and malignant neoplasms (50 [13.6%]). In-hospital death occurred in 142 (38.0%) patients. In the multivariable model older age (Relative Risk [RR] 1.06 [1.04-1. 09] per year), diabetes (RR 1.56 [1.05-2.02]), chronic obstructive pulmonary disease (RR 1.82 [1.13-2.35]), higher values of lactic dehydrogenase and C-reactive protein were independently associated with in-hospital mortality.
conclusionIn this retrospective single-center study, diabetes was independently associated with a higher in-hospital mortality. More intensive surveillance of patients with this condition is to be warranted.
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