Evidence map›Paper›PMID 32776193›Full record

ArticleHistochemistry and cell biology2020

Low fluid shear stress promoted ciliogenesis via Dvl2 in hUVECs.

Xin Sheng, Yan Sheng, Shuanglin Gao, Fang Fan, Junhua Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Histochemistry and cell biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Vascular mechanotransduction.Physiological reviews · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xin ShengDepartment of Biochemistry, Zunyi Medical University, Zunyi, 563000, People's Republic of China. xshengbio@163.com.ORCID http://orcid.org/0000-0002-7700-5606
Yan ShengLaboratory of Basic Medical Morphology, Zunyi Medical University, Zunyi, 563000, People's Republic of China.
Shuanglin GaoDepartment of Biochemistry, Zunyi Medical University, Zunyi, 563000, People's Republic of China.
Fang FanDepartment of Biochemistry, Zunyi Medical University, Zunyi, 563000, People's Republic of China.
Junhua WangDepartment of Biochemistry, Zunyi Medical University, Zunyi, 563000, People's Republic of China.
Zunyi Medical University · CN

Funding

National Natural Science Foundation of China 31360278
6 · The paper itself

Abstract

This study aims to explore the mechanism of fluid shear stress in regulating the primary cilia assembly or disassembly in human umbilical vein endothelial cells (hUVECs) using microfluidic chamber experiments. Immunofluorescence analysis showed that primary cilia assembled under disturbed fluid shear stress (DF) of 1 dyne/cm

Indexed as

MicrofluidicsStress, MechanicalCells, CulturedCiliaDishevelled ProteinsHumansHuman Umbilical Vein Endothelial CellsDishevelled ProteinsDVL2 protein, humanDvl2Fluid shear stresshUVECsPrimary ciliaWnt signaling pathway

Identifiers

PMID32776193
OpenAlexW3049349212

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.