Evidence map›Paper›PMID 32776179›Full record

ReviewCurrent HIV/AIDS reports2020

A Cascade of Interventions to Promote Adherence to Antiretroviral Therapy in African Countries.

Rebecca Jopling, Primrose Nyamayaro, Lena S Andersen, Ashraf Kagee, Jessica E Haberer, Melanie Amna Abas

Open access · hybridAbstract readReview
In one paragraph

Review in Current HIV/AIDS reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Rebecca JoplingHealth Service & Population Research Department, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Primrose NyamayaroDepartment of Psychiatry, University of Zimbabwe College of Health Sciences, Mazowe Street, Avondale, Harare, Zimbabwe.
Lena S AndersenHIV Mental Health Research Unit, Division of Neuropsychiatry, Department of Psychiatry and Mental Health, University of Cape Town, Groote Schuur Hospital Anzio Road, Observatory, Cape Town, South Africa.
Ashraf KageeDepartment of Psychology, Stellenbosch University, Stellenbosch, 7602, South Africa.
Jessica E HabererCenter for Global Health, Massachusetts General Hospital, Harvard Medical School, Boston, USA.
Melanie Amna AbasHealth Service & Population Research Department, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK. melanie.abas@kcl.ac.uk.ORCID 0000-0003-1716-5584
King's College London · GBHarvard University · USStellenbosch University · ZAUniversity of Cape Town · ZAUniversity of Zimbabwe · ZW

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ARTHUR Y KIM · 2004 to 2026
$94.4M
The TENDAI study: Task shifting to treat depression and HIV medication nonadherence in low resource settings: Supplementary funding to fulfill the scope of work after Covid-19 delaysR01MH114708 · NIMH · KING'S COLLEGE LONDON · PI ABAS, MELANIE AMNA, O'CLEIRIGH, CONALL MICHAEL · 2018 to 2023
$4.1M
NIAID NIH HHS P30 AI060354NIMH NIH HHS R01 MH114708
6 · The paper itself

Abstract

purpose of reviewWe reviewed interventions to improve uptake and adherence to antiretroviral therapy (ART) in African countries in the Treat All era. RECENT

findingsART initiation can be improved by facilitated rapid receipt of first prescription, including community-based linkage and point-of-care strategies, integration of HIV care into antenatal care and peer support for adolescents. For people living with HIV (PLHIV) on ART, scheduled SMS reminders, ongoing intensive counselling for those with viral non-suppression and economic incentives for the most deprived show promise. Adherence clubs should be promoted, being no less effective than facility-based care for stable patients. Tracing those lost to follow-up should be targeted to those who can be seen face-to-face by a peer worker. Investment is needed to promote linkage to initiating ART and for differentiated approaches to counselling for youth and for those with identified suboptimal adherence. More evidence from within Africa is needed on cost-effective strategies to identify and support PLHIV at an increased risk of non-adherence across the treatment cascade.

Indexed as

Drug MonitoringPsychosocial Support SystemsAdolescentAdultAfricaAnti-HIV AgentsCounselingFemaleHIV InfectionsHumansMalePregnancyYoung AdultAnti-HIV AgentsAdherenceAntiretroviral therapy (ART)ART initiationHIVInterventionsRetention in careReview

Identifiers

PMID32776179
PMCPMC7497365
OpenAlexW3048670358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.