Evidence map›Paper›PMID 32775825›Full record

ArticleKidney international reports2020

Supervised Exercise Intervention and Overall Activity in CKD.

Mindy M Pike, Aseel Alsouqi, Samuel A E Headley, Katherine Tuttle, Elizabeth Elspeth Evans, Charles M Milch, Kelsey Anne Moody, Michael Germain, Thomas G Stewart, Loren Lipworth and 3 more

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Review
  7. The Authors Reply.Kidney international reports · 2020
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Mindy M PikeVanderbilt O'Brien Kidney Center, Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Aseel AlsouqiVanderbilt O'Brien Kidney Center, Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Samuel A E HeadleyDepartment of Exercise Science and Athletic Training, Springfield College, Springfield, Massachusetts, USA.
Katherine TuttleKidney Research Institute, Division of Nephrology, Department of Medicine, University of Washington, Seattle, Washington, USA.
Elizabeth Elspeth EvansDepartment of Exercise Science and Athletic Training, Springfield College, Springfield, Massachusetts, USA.
Charles M MilchDepartment of Exercise Science and Athletic Training, Springfield College, Springfield, Massachusetts, USA.
Kelsey Anne MoodyDepartment of Exercise Science and Athletic Training, Springfield College, Springfield, Massachusetts, USA.
Michael GermainDepartment of Nephrology, Bay State Medical Center, Springfield, Massachusetts, USA.
Thomas G StewartDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Loren LipworthVanderbilt O'Brien Kidney Center, Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Jonathan HimmelfarbKidney Research Institute, Division of Nephrology, Department of Medicine, University of Washington, Seattle, Washington, USA.
T Alp IkizlerVanderbilt O'Brien Kidney Center, Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Cassianne Robinson-CohenVanderbilt O'Brien Kidney Center, Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Vanderbilt University Medical Center · USSpringfield College · USUniversity of Washington · USBaystate Medical Center · US

Funding

Institute of Translational Health SciencesUL1TR000423 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$49.4M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
PILOT STUDY--CLINICAL NUTRITION RESEARCHP30DK035816 · NIDDK · UNIVERSITY OF WASHINGTON · PI Ellen A Schur · 1986 to 2026
$30.4M
Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALVIN C POWERS · 2012 to 2026
$29.3M
Structural Biology Facility CoreP30ES000267 · NIEHS · VANDERBILT UNIVERSITY · PI GUENGERICH, F PETER · 1985 to 2014
$20.3M
NRSA Training CoreTL1TR002244 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Julie A. Bastarache · 2017 to 2026
$4.6M
Oxidative Stress in Chronic Kidney DiseaseR01HL070938 · NHLBI · UNIVERSITY OF WASHINGTON · PI HIMMELFARB, JONATHAN, IKIZLER, TALAT ALP · 2003 to 2012
$3.2M
Nutrition and Metabolism in Dialysis PatientsK24DK062849 · NIDDK · VANDERBILT UNIVERSITY · PI IKIZLER, TALAT ALP · 2003 to 2012
$1.6M
NCATS NIH HHS TL1 TR002244NCATS NIH HHS UL1 TR000423NCATS NIH HHS UL1 TR000445NHLBI NIH HHS R01 HL070938NIDDK NIH HHS K24 DK062849NIDDK NIH HHS P30 DK020593NIDDK NIH HHS P30 DK035816NIEHS NIH HHS P30 ES000267
6 · The paper itself

Abstract

introductionPatients are often instructed to engage in multiple weekly sessions of exercise to increase physical activity. We aimed to determine whether assignment to a supervised exercise regimen increases overall weekly activity in individuals with chronic kidney disease (CKD).

methodsWe performed a secondary analysis of a pilot randomized 2 × 2 factorial design trial examining the effects of diet and exercise (10%-15% reduction in caloric intake, 3 supervised exercise sessions/wk, combined diet restriction/exercise, and control). Activity was measured as counts detected by accelerometer. Counts data were collected on all days for which an accelerometer was worn at baseline, month 2, and month 4 follow-up. The primary outcome was a relative change from baseline in log-transformed counts/min. Generalized estimating equations were used to compare the primary outcome in individuals in the exercise group and the nonexercise group.

resultsWe examined 111 individuals randomized to aerobic exercise or usual activity (n = 48 in the exercise group and n = 44 controls). The mean age was 57 years, 42% were female, and 28% were black. Median overall adherence over all time was 73%. Median (25th, 75th percentile) counts/min over nonsupervised exercise days at months 2 and 4 were 237.5 (6.5, 444.4) for controls and 250.9 (7.7, 529.8) for the exercise group (

conclusionEngaging in a supervised exercise program does not increase overall weekly physical activity in individuals with stage 3 to 4 CKD.

Indexed as

accelerometerchronic kidney diseasecounts per minuteexercisephysical activityrandomized

Identifiers

PMID32775825
PMCPMC7403561
OpenAlexW3034238433

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.