ArticleKidney international reports2020
Urinary Sodium-to-Potassium Ratio and Blood Pressure in CKD.
Article in Kidney international reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Associations of 24-Hour Urinary Sodium, Potassium Excretion and Sodium-to-Potassium Ratio With Longitudinal Home Blood Pressure Control in Patients With Apparent Treatment-Resistant Hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2026Observational
- Development and Evaluation of a Urinary Na/K Ratio Prediction Model: A Systematic Comparison from Attention-Based Deep Learning to Classical Ensemble Approaches.Bioengineering (Basel, Switzerland) · 2026Article
- Association of Dietary Sodium and Potassium With Blood Pressure and Proteinuria in Africans With Kidney Disease.Kidney international reports · 2025Article
- Association between the urinary sodium-to-potassium ratio and apparent treatment-resistant hypertension in Japanese patients with non-dialysis dependent chronic kidney disease: the Fukuoka Kidney disease Registry study.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Associations and mediators of estimated sodium intake with cardiovascular mortality: data based on a national population cohort.BMC medicine · 2025Article
- Higher Nocturnal Blood Pressure and Blunted Nocturnal Dipping Are Associated With Decreased Daytime Urinary Sodium and Potassium Excretion in Patients With CKD.Kidney international reports · 2024Article
- Article
- Characteristics of urinary sodium excretion in patients with chronic kidney disease in Jiangsu, China.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Focus on the Possible Role of Dietary Sodium, Potassium, Phosphate, Magnesium, and Calcium on CKD Progression.Journal of clinical medicine · 2021Review
- Adherence to the Kidney Disease: Improving Global Outcomes CKD Guideline in Nephrology Practice Across Countries.Kidney international reports · 2021Article
- Sodium and Potassium Intake: A New Statistical Model to Test Their Effects on Health Outcomes.Kidney international reports · 2020Article
- The Authors Reply.Kidney international reports · 2020Article
Corrections and comments
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Authors and funding
15 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIn the general population, urinary sodium-to-potassium (uNa/K) ratio associates more strongly with high blood pressure (BP) than either urinary sodium or potassium alone. Whether this is also the case among patients with chronic kidney disease (CKD) is unknown.
methodsWe studied the associations of spot urine sodium-to-creatinine (uNa/Cr), potassium-to-creatinine (uK/Cr), and uNa/K ratios with a single office BP reading in 1660 patients with moderate to severe CKD at inclusion in the CKD-REIN cohort.
resultsPatients' median age was 68 (interquartile range [IQR], 59-76) years; most were men (65%), had moderate CKD (57%), and albuminuria (72%). Mean systolic and diastolic BP was 142/78 mm Hg. Spot uNa/Cr and uNa/K ratios were positively associated with systolic, mean arterial, and pulse pressures. The mean adjusted difference in systolic BP between the highest and the lowest quartile (Q4 vs
conclusionIn patients with CKD, higher urinary sodium excretion is associated with higher BP, but unlike in general population, lower potassium excretion is not. Urinary Na/K does not add significant value in assessing high BP risk, except perhaps for hypertension control assessment.
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