Evidence map›Paper›PMID 32775766›Full record

ArticleAmerican journal of ophthalmology case reports2020

Orbital myeloid sarcoma (chloroma): Report of 2 cases and literature review.

Mohammad A AlSemari, Marianna Perrotta, Camilla Russo, Hind M Alkatan, A Maktabi, S Elkhamary, Rosa Maria Di Crescenzo, Massimo Mascolo, Andrea Elefante, Luca Rombetto and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in American journal of ophthalmology case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Extramedullary Relapse ofInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Isolated orbital granulocytic sarcoma.Eye (London, England) · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Mohammad A AlSemariKing Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Marianna PerrottaDepartment of Advanced Biomedical Sciences, University "Federico II", Naples, Italy.
Camilla RussoDepartment of Advanced Biomedical Sciences, University "Federico II", Naples, Italy.
Hind M AlkatanDepartment of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
A MaktabiKing Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
S ElkhamaryKing Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Rosa Maria Di CrescenzoDepartment of Advanced Biomedical Sciences - Pathology Unit, University "Federico II", Naples, Italy.
Massimo MascoloDepartment of Advanced Biomedical Sciences - Pathology Unit, University "Federico II", Naples, Italy.
Andrea ElefanteDepartment of Advanced Biomedical Sciences, University "Federico II", Naples, Italy.
Luca RombettoDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University "Federico II", Naples, Italy.
Raffaella CapassoDepartment of Medicine and Health Sciences "Vincenzo Tiberio", Università degli Studi del Molise, Campobasso, Italy.
Diego StrianeseKing Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Federico II University Hospital · ITKing Khaled Eye Specialist Hospital · SAKing Saud University · SAUniversity of Molise · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMyeloid sarcoma (MS) of the orbit is an uncommon condition in occurring in children, generally coupled to myeloproliferative neoplasms. OBSERVATIONS: We describe two rare cases of orbital MS in young boys with aggressive local symptoms but without evidence of acute myeloid leukemia (AML), both patients underwent orbitotomy for gross-tumor resection and biopsy. At follow up, there was no evidence of recurrence nor evolution of the myeloproliferative neoplasms clinically and by radiological and laboratory work-up. We also provide a detailed description of the magnetic resonance imaging presentation, with an extensive pathological analysis correlation. CONCLUSIONS AND IMPORTANCE: A comprehensive revision of the literature on isolated orbital MS was carried out with particular emphasis on clues for differential diagnosis and treatment options, stressing the need to consider MS even in the absence of sign and symptoms of an underlying myeloproliferative disorders.

Indexed as

Acute myeloid leukemiaMagnetic resonance imagingMyeloid sarcomaOrbital pathologyPediatric tumor

Identifiers

PMID32775766
PMCPMC7397738
OpenAlexW3041212593

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.