Evidence map›Paper›PMID 32775708›Full record

ArticleSynthetic and systems biotechnology2020

Structure-guided manipulation of the regioselectivity of the cyclosporine A hydroxylase CYP-sb21 from

Fengwei Li, Li Ma, Xingwang Zhang, Jingfei Chen, Feifei Qi, Yinyue Huang, Zepeng Qu, Lishan Yao, Wei Zhang, Eung-Soo Kim and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Synthetic and systems biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Characterization of a CYP107 family vitamin DArchives of biochemistry and biophysics · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fengwei LiState Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong, 266237, China.
Li MaState Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong, 266237, China.
Xingwang ZhangState Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong, 266237, China.
Jingfei ChenShandong Provincial Key Laboratory of Synthetic Biology, CAS Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, 266101, China.
Feifei QiShandong Provincial Key Laboratory of Synthetic Biology, CAS Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, 266101, China.
Yinyue HuangState Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong, 266237, China.
Zepeng QuShandong Provincial Key Laboratory of Synthetic Biology, CAS Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, 266101, China.
Lishan YaoShandong Provincial Key Laboratory of Synthetic Biology, CAS Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, 266101, China.
Wei ZhangState Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong, 266237, China.
Eung-Soo KimDepartment of Biological Engineering, Inha University, Incheon, 22212, South Korea.
Shengying LiState Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong, 266237, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cytochrome P450 enzyme CYP-sb21 from the rare actinomycete

Indexed as

Crystal structureCyclosporine ACytochrome P450 monooxygenaseHair growth stimulatorRegioselectivity

Identifiers

PMID32775708
PMCPMC7394738

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.