Evidence map›Paper›PMID 32775463›Full record

ArticleJournal of diabetes research2020

Sex-Specific Association of Serum Uric Acid Level and Change in Hyperuricemia Status with Risk of Type 2 Diabetes Mellitus: A Large Cohort Study in China.

Yanmei Lou, Pei Qin, Changyi Wang, Jianping Ma, Xiaolin Peng, Shan Xu, Hongen Chen, Dan Zhao, Li Wang, Dechen Liu and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Yanmei Lou *Department of Health Management, Beijing Xiaotangshan Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-5107-5331
Pei Qin *Department of Epidemiology and Health Statistics, School of Public Health, Shenzhen University Health Science Center, Shenzhen, Guangdong, China.ORCID https://orcid.org/0000-0003-2303-0379
Changyi WangDepartment of Non-Communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease, Shenzhen, Guangdong, China.
Jianping MaDepartment of Non-Communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease, Shenzhen, Guangdong, China.
Xiaolin PengDepartment of Non-Communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease, Shenzhen, Guangdong, China.ORCID https://orcid.org/0000-0002-0958-7042
Shan XuDepartment of Non-Communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease, Shenzhen, Guangdong, China.
Hongen ChenDepartment of Non-Communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease, Shenzhen, Guangdong, China.
Dan ZhaoDepartment of Non-Communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease, Shenzhen, Guangdong, China.
Li WangDepartment of Non-Communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease, Shenzhen, Guangdong, China.
Dechen LiuDepartment of Epidemiology and Health Statistics, School of Public Health, Zhengzhou University, Zhengzhou, Henan, China.ORCID https://orcid.org/0000-0002-4136-4148
Yang LiDepartment of Epidemiology and Health Statistics, School of Public Health, Shenzhen University Health Science Center, Shenzhen, Guangdong, China.ORCID https://orcid.org/0000-0003-1495-5230
Ping ZhaoDepartment of Health Management, Beijing Xiaotangshan Hospital, Beijing, China.
Dezhu HanBeijing Fangshan District Yanshan Commission of Culture, Health and Family Planning, Beijing, China.
Dongsheng HuDepartment of Epidemiology and Health Statistics, School of Public Health, Shenzhen University Health Science Center, Shenzhen, Guangdong, China.ORCID https://orcid.org/0000-0002-9998-8041
Fulan HuDepartment of Epidemiology and Health Statistics, School of Public Health, Shenzhen University Health Science Center, Shenzhen, Guangdong, China.ORCID https://orcid.org/0000-0002-2386-1503
Shenzhen Nanshan Center for Chronic Disease Control · CNShenzhen University Health Science Center · CNTang Hospital · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConflicting findings have been reported regarding the sex-specific association between serum uric acid (SUA) level and type 2 diabetes mellitus (T2DM) risk, and no study has explored the association between the change in hyperuricemia status and T2DM risk. The study was aimed at exploring the sex-specific association of baseline SUA and changes in hyperuricemia status with T2DM risk.

methodsWe included 37,296 eligible adults without T2DM at the first examination who attended the baseline examination and at least one follow-up annual examination. Cox and logistic regression models were used to calculate hazard ratios (HRs) and odds ratios (ORs) with their 95% confidence intervals (CIs) for T2DM risk associated with baseline SUA and the change in hyperuricemia status, respectively.

resultsDuring a median follow-up of 3.09 years, of 37,296 eligible adults, 2,263 developed T2DM. Compared with the first SUA quartile, higher quartiles were associated with an increased risk of T2DM in women (HR 1.78, 95% CI 1.17-2.71 for Q3 and 1.93, 1.27-2.93 for Q4;

conclusionsBaseline SUA and the change in hyperuricemia status were associated with T2DM risk only among women. The findings suggest the importance of monitoring SUA levels and maintaining them within a normal range for preventing or reducing incident T2DM in Chinese women.

Indexed as

AdultChinaCohort StudiesDiabetes Mellitus, Type 2FemaleFollow-Up StudiesHumansHyperuricemiaMaleMiddle AgedProportional Hazards ModelsRisk FactorsSex FactorsUric AcidYoung AdultUric Acid

Identifiers

PMID32775463
PMCPMC7396085
OpenAlexW3045296437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.