Evidence map›Paper›PMID 32775304›Full record

ReviewFrontiers in cellular and infection microbiology2020

Virus-Specific T Cell Therapies for HIV: Lessons Learned From Hematopoietic Stem Cell Transplantation.

Ping-Hsien Lee, Michael D Keller, Patrick J Hanley, Catherine M Bollard

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. EfficientFrontiers in immunology · 2023
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ping-Hsien LeeCenter for Cancer and Immunology Research, Children's National Hospital, Washington, DC, United States.
Michael D KellerCenter for Cancer and Immunology Research, Children's National Hospital, Washington, DC, United States.
Patrick J HanleyCenter for Cancer and Immunology Research, Children's National Hospital, Washington, DC, United States.
Catherine M BollardCenter for Cancer and Immunology Research, Children's National Hospital, Washington, DC, United States.
Children's National · USGeorge Washington University · US

Funding

BELIEVE: Bench to Bed Enhanced Lymphocyte Infusions to Engineer Viral EradicationUM1AI126617 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI JONES, R. BRAD, NIXON, DOUGLAS F · 2016 to 2020
$28.1M
PR1-specific CB T cells for Patients with Myeloid MalignanciesP01CA148600 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BOLLARD, CATHERINE M., SHPALL, ELIZABETH J · 2011 to 2022
$24.4M
Targeting MRDP01CA225618 · NCI · JOHNS HOPKINS UNIVERSITY · PI Catherine M. Bollard, KENNETH R COOKE · 2019 to 2026
$15.1M
The District of Columbia Developmental Center for AIDS Research (DC D-CFAR)P30AI087714 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI GREENBERG, ALAN EDWARD · 2010 to 2014
$8.4M
HIV-specific ex-vivo expanded T cell therapy (HXTC) to Deplete the Latent Reservoir of Persistent HIV InfectionR01HL132791 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOLLARD, CATHERINE M., MARGOLIS, DAVID M. · 2016 to 2020
$3.8M
Adoptive Immunotherapy for the Treatment of Viral Infections in Primary Immunodeficiency DisordersK23HL136783 · NHLBI · CHILDREN'S RESEARCH INSTITUTE · PI KELLER, MICHAEL DANIEL · 2017 to 2019
$614k
NCI NIH HHS P01 CA148600NCI NIH HHS P01 CA225618NHLBI NIH HHS K23 HL136783NHLBI NIH HHS R01 HL132791NIAID NIH HHS P30 AI087714NIAID NIH HHS UM1 AI126617
6 · The paper itself

Abstract

Human immunodeficiency virus (HIV) has caused millions of deaths and continues to threaten the health of millions of people worldwide. Despite anti-retroviral therapy (ART) substantially alleviating severity and limiting transmission, HIV has not been eradicated and its persistence can lead to other health concerns such as cancer. The only two cases of HIV cure to date are HIV

Indexed as

Epstein-Barr Virus InfectionsHematopoietic Stem Cell TransplantationHIV InfectionsHerpesvirus 4, HumanHumansT-Lymphocyteshematopoietic stem cell transplantationHIVimmunotherapylatent reservoirT cells

Identifiers

PMID32775304
PMCPMC7381350
OpenAlexW3040656238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.