ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2020
Flexible Fiber Probe for Efficient Neural Stimulation and Detection.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The trial behind it
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Who cites it
16 citing papers in PubMed, 54 citations in OpenAlex.
- Weaving Intelligence: Thermally Drawn Multimaterial Fibers Toward AI-Enabled Smart Textiles.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Structurally engineered ultrasoft PEDOT:PSS fiber microelectrodes with enhanced electrochemical performance for neural interfaces.Science advances · 2026Article
- Monolithic multimodal neural probes for sustained stimulation and long-term neural recording.Science advances · 2025Article
- Flexible multimaterial fibers in modern biomedical applications.National science review · 2024Review
- Application of Optogenetics in Neurodegenerative Diseases.Cellular and molecular neurobiology · 2024Review
- Self-Healable Multifunctional Fibers via Thermal Drawing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Impact of Impedance Levels on Recording Quality in Flexible Neural Probes.Sensors (Basel, Switzerland) · 2024Article
- Micro/nanosystems for controllable drug delivery to the brain.Innovation (Cambridge (Mass.)) · 2024Review
- Piezoelectric fibers for flexible and wearable electronics.Frontiers of optoelectronics · 2023Review
- Electrospun PVDF-based piezoelectric nanofibers: materials, structures, and applications.Nanoscale advances · 2023Review
- A 'Moore's law' for fibers enables intelligent fabrics.National science review · 2023Review
- Laser Machined Fiber-based Microprobe: Application in Microscale Electroporation.Advanced fiber materials · 2022Article
- Multiplexed Monitoring of Neurochemicals via Electrografting-Enabled Site-Selective Functionalization of Aptamers on Field-Effect Transistors.Analytical chemistry · 2022Article
- Biocompatible and Biodegradable Polymer Optical Fiber for Biomedical Application: A Review.Biosensors · 2021Review
- Review
- Flexible Fiber Probe for Efficient Neural Stimulation and Detection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Functional probes are a leading contender for the recognition and manipulation of nervous behavior and are characterized by substantial scientific and technological potential. Despite the recent development of functional neural probes, a flexible biocompatible probe unit that allows for long-term simultaneous stimulation and signaling is still an important task. Here, a category of flexible tiny multimaterial fiber probes (<0.3 g) is described in which the metal electrodes are regularly embedded inside a biocompatible polymer fiber with a double-clad optical waveguide by thermal drawing. Significantly, this arrangement enables great improvement in mechanical properties, achieves high optical transmission (>90%), and effectively minimizes the impedance (by up to one order of magnitude) of the probe. This ability allows to realize long-term (at least 10 weeks) simultaneous optical stimulation and neural recording at the single-cell level in behaving mice with signal-to-noise ratio (SNR = 30 dB) that is more than 6 times that of the benchmark probe such as an all-polymer fiber.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.