Evidence map›Paper›PMID 32774879›Full record

ArticleEvolution letters2020

Adaptation via pleiotropy and linkage: Association mapping reveals a complex genetic architecture within the stickleback

Sophie L Archambeault, Luis R Bärtschi, Aurélie D Merminod, Catherine L Peichel

Open access · goldAbstract read
In one paragraph

Article in Evolution letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Microevolutionary change in wild stickleback: Using integrative time-series data to infer responses to selection.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  13. Article
  14. Article
  15. Complex evolutionary processes maintain an ancient chromosomal inversion.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  16. A pleiotropic hypoxia-sensitiveScience advances · 2022
    Article
  17. Article
  18. Genetics of adaptation.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  19. Testing for fitness epistasis in a transplant experiment identifies a candidate adaptive locus inPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Sophie L ArchambeaultInstitute of Ecology and Evolution University of Bern Bern 3012 Switzerland.ORCID https://orcid.org/0000-0001-9409-7541
Luis R BärtschiInstitute of Ecology and Evolution University of Bern Bern 3012 Switzerland.
Aurélie D MerminodInstitute of Ecology and Evolution University of Bern Bern 3012 Switzerland.
Catherine L PeichelInstitute of Ecology and Evolution University of Bern Bern 3012 Switzerland.ORCID https://orcid.org/0000-0002-7731-8944
University of Bern · CH

Funding

TRAINING IN MOLECULAR AND CELLULAR BIOLOGYT32GM007270 · NIGMS · UNIVERSITY OF WASHINGTON · PI RAIBLE, DAVID W · 1985 to 2020
$21.0M
NIGMS NIH HHS T32 GM007270
6 · The paper itself

Abstract

Genomic mapping of the loci associated with phenotypic evolution has revealed genomic "hotspots," or regions of the genome that control multiple phenotypic traits. This clustering of loci has important implications for the speed and maintenance of adaptation and could be due to pleiotropic effects of a single mutation or tight genetic linkage of multiple causative mutations affecting different traits. The threespine stickleback (

Indexed as

Adaptationassociation mappingEctodysplasin (Eda)Gasterosteus aculeatuslateral line neuromastslateral plateslinkagepleiotropythreespine stickleback

Identifiers

PMID32774879
PMCPMC7403726
OpenAlexW3031658553

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.