Evidence map›Paper›PMID 32774870›Full record

ArticleJournal of pharmaceutical policy and practice2020

Sale of WHO AWaRe groups antibiotics without a prescription in Pakistan: a simulated client study.

Zikria Saleem, Mohamed Azmi Hassali, Brian Godman, Munazzah Fatima, Zeenia Ahmad, Areeba Sajid, Inaam Ur Rehman, Muhammad Umer Nadeem, Zaida Javaid, Madeeha Malik and 1 more

Abstract read
In one paragraph

Article in Journal of pharmaceutical policy and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Non-prescription antibiotics dispensing for common infections using simulated patients.Exploratory research in clinical and social pharmacy · 2026
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  16. Longevity of immune response after a single dose of typhoid conjugate vaccine against Salmonella Typhi among children in Hyderabad, Pakistan.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zikria SaleemSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, George Town, Malaysia.
Mohamed Azmi HassaliSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, George Town, Malaysia.
Brian GodmanSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, George Town, Malaysia.
Munazzah FatimaUniversity College of Pharmacy, University of the Punjab, Lahore, Pakistan.
Zeenia AhmadUniversity College of Pharmacy, University of the Punjab, Lahore, Pakistan.
Areeba SajidUniversity College of Pharmacy, University of the Punjab, Lahore, Pakistan.
Inaam Ur RehmanUniversity College of Pharmacy, University of the Punjab, Lahore, Pakistan.
Muhammad Umer NadeemUniversity College of Pharmacy, University of the Punjab, Lahore, Pakistan.
Zaida JavaidPunjab Institute of Cardiology, Lahore, Pakistan.
Madeeha MalikHamdard Institute of Pharmaceutical Sciences, Hamdard University, Islamabad, Pakistan.
Azhar HussainHamdard Institute of Pharmaceutical Sciences, Hamdard University, Islamabad, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionResistant strains of bacteria are rapidly emerging with increasing inappropriate use of antibiotics rendering them less efficacious. Self-purchasing of antibiotics particularly for viral infections is a key driver of inappropriate use, especially in lower- and middle-income countries. There is a particular issue in countries such as Pakistan. Consequently, there is a need to assess current rates of self-purchasing especially for reserve antibiotics to guide future policies.

aimsAssess the extent of current antibiotic sales without a prescription in urban areas of Pakistan. METHODOLOGY: A multicenter cross-sectional study was conducted in different areas of Punjab, Pakistan using Simulated Client technique. The investigators demanded different predefined antibiotics from WHO AWaRe groups without prescription. Three levels of demand were used to convince the pharmacy staff in order to dispense the antibiotic without a prescription. A data collection form was completed by simulated clients within 15 min of each visit.

resultsOverall 353 pharmacies and medical stores were visited out of which 96.9% pharmacies and medical stores dispensed antibiotics without demanding a prescription (82.7% at demand level 1 and 14.2% at demand level 2), with only 3.1% of pharmacies refusing to dispense antibiotics. The most frequently dispensed antibiotic was ciprofloxacin (22.1%). Surprisingly, even the reserve group antibiotics were also dispensed without a prescription. In only 25.2% visits, pharmacy staff guided patients about the use of antibiotics, and in only 11.0% pharmacists enquired about other medication history.

conclusionCurrently, antibiotics are easily acquired without a legitimate prescription in Pakistan. There is a need for strict adherence to regulations combined with a multi-dimensional approach to enhance appropriate dispensing of antibiotics and limit any dispensing of WHO restricted antibiotics without a prescription.

Indexed as

AntibioticsPakistanSale without prescriptionSimulated client

Identifiers

PMID32774870
PMCPMC7397594

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.