Evidence map›Paper›PMID 32774820›Full record

ArticleNeurology international2020

Determining the association between polymorphisms of the

Cempaka Thursina, Dian Kesumapramudya Nurputra, Indra Sari Kusuma Harahap, Nur Imma Fatimah Harahap, Nihayatus Sa'adah, Samekto Wibowo, Sri Sutarni, Ahmad Hamim Sadewa, Hermawan Hanjaya, Hisahide Nishio

Open access · goldAbstract read
In one paragraph

Article in Neurology international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Attention-deficit/hyperactive disorder updates.Frontiers in molecular neuroscience · 2022
    Review
  4. ADHD: Reviewing the Causes and Evaluating Solutions.Journal of personalized medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Cempaka ThursinaDoctoral Programme of Medical and Health Science, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Dian Kesumapramudya NurputraDepartment of Pediatrics, Faculty of Medicine Universitas Gadjah Mada, Yogyakarta, Indonesia.
Indra Sari Kusuma HarahapDepartment of Neurology, Faculty of Medicine Universitas Gadjah Mada, Yogyakarta, Indonesia.
Nur Imma Fatimah HarahapDepartment of Community Medicine and Social Health Care Science, Kobe University Graduate School of Medicine, Kobe, Japan.
Nihayatus Sa'adahDepartment of Biochemistry, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Samekto WibowoDepartment of Neurology, Faculty of Medicine Universitas Gadjah Mada, Yogyakarta, Indonesia.
Sri SutarniDepartment of Neurology, Faculty of Medicine Universitas Gadjah Mada, Yogyakarta, Indonesia.
Ahmad Hamim SadewaDepartment of Biochemistry, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Hermawan HanjayaDepartment of Neurology, Faculty of Medicine Universitas Gadjah Mada, Yogyakarta, Indonesia.
Hisahide NishioDepartment of Community Medicine and Social Health Care Science, Kobe University Graduate School of Medicine, Kobe, Japan.
Universitas Gadjah Mada · IDKobe University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Attention deficit hyperactivity disorder (ADHD) is one of the most common neurobehavioural in the children. Genetic factor is known one of the factors which contributed in ADHD development. VNTR polymorphism in 3'UTR exon 15 of DAT1 gene and exon 3 of DRD4 gene are reported to be associated in ADHD. In this study we examine the association of ADHD with VNTR polymorphism of DAT1 and DRD4 gene in Indonesian children. Sixty-five ADHD children and 70 normal children (6-13 years of age), were included in the study, we matched by age and gender. ADHD was diagnosed by DSM-IV. We performed a casecontrol study to found the association between ADHD and VNTR polymorphism of DAT1 and DRD4 genes. The 10-repeat allele of DAT1 and 2-repeat allele of DRD4 were higher in Indonesian children. Although the frequency of these allele was higher, but it was similar both in ADHD and control groups. Neither DAT1 nor DRD4 gene showed showed significant difference in genotype distribution and frequency allele between both groups (p > 0.05)

Indexed as

ADHDcase-control studyChildrenDATDRD4Indonesian

Identifiers

PMID32774820
PMCPMC7378541
OpenAlexW3041731256

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.