ArticleAmerican journal of translational research2020
Human coilin interacting nuclear ATPase protein in cancer: uncovering new insights into pathogenesis and therapy.
Article in American journal of translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- Coilin Affects the Prognosis of Hepatocellular Carcinoma Through Cell Cycle and Apoptosis.Journal of hepatocellular carcinoma · 2025Article
- hCINAP serves a critical role in hypoxia‑induced cardiomyocyte apoptosis via modulating lactate production and mitochondrial‑mediated apoptosis signaling.Molecular medicine reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A deeper understanding of tumor pathogenesis has revolutionized cancer treatment strategies. The discovery of human coilin interacting nuclear ATPase protein (hCINAP) and increasing experimental research over the past 15 years have provided us with new insights into the diagnoses, prognoses, and therapeutic approaches of cancer. In the current review, hCINAP's effect on tumor growth, cell viability, invasion, metastasis, and drug resistance is summarized. In addition, an overview is given of the underlying mechanisms involved, including regulation of signaling pathways, ribosome biogenesis, metabolism, as well as DNA damage repair. Finally, hCINAP-based therapeutic approaches are examined, with the goal of improving efficacy of cancer treatments. This review can, therefore, serve as a reference for further hCINAP-related research and clinical trials, and we advocate those approaches to be initiated without delay.
Indexed as
Identifiers
32774758PMC7407739W3049379131What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.