Evidence map›Paper›PMID 32774732›Full record

ArticleAmerican journal of translational research2020

Electrospun nanofibrous membrane of fish collagen/polycaprolactone for cartilage regeneration.

Zihao Jia, Hao Li, Runfeng Cao, Kaiyan Xiao, Jia Lu, Dandan Zhao, Zongxin Wang, Yongjun Zhang, Jie Chen, Wei Zhang and 1 more

Abstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Porous fish collagen for cartilage tissue engineering.American journal of translational research · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zihao JiaInstitute of Plastic Surgery, Shandong Provincial Key Laboratory of Plastic and Microscopic Repair Technology, Weifang Medical University Shandong, P. R. China.
Hao LiInstitute of Plastic Surgery, Shandong Provincial Key Laboratory of Plastic and Microscopic Repair Technology, Weifang Medical University Shandong, P. R. China.
Runfeng CaoShanghai Key Laboratory of Tissue Engineering, Shanghai 9th People's Hospital, School of Medicine, Shanghai Jiao Tong University Shanghai, P. R. China.
Kaiyan XiaoShanghai Key Laboratory of Tissue Engineering, Shanghai 9th People's Hospital, School of Medicine, Shanghai Jiao Tong University Shanghai, P. R. China.
Jia LuShanghai Key Laboratory of Tissue Engineering, Shanghai 9th People's Hospital, School of Medicine, Shanghai Jiao Tong University Shanghai, P. R. China.
Dandan ZhaoInstitute of Plastic Surgery, Shandong Provincial Key Laboratory of Plastic and Microscopic Repair Technology, Weifang Medical University Shandong, P. R. China.
Zongxin WangInstitute of Plastic Surgery, Shandong Provincial Key Laboratory of Plastic and Microscopic Repair Technology, Weifang Medical University Shandong, P. R. China.
Yongjun ZhangDepartment of Medical Cosmetology, The First Affiliated Hospital of Xinxiang Medical University Henan, P. R. China.
Jie ChenShanghai Key Laboratory of Tissue Engineering, Shanghai 9th People's Hospital, School of Medicine, Shanghai Jiao Tong University Shanghai, P. R. China.
Wei ZhangInstitute of Plastic Surgery, Shandong Provincial Key Laboratory of Plastic and Microscopic Repair Technology, Weifang Medical University Shandong, P. R. China.
Ru ChenDepartment of Breast Surgery, Hainan General Hospital, Hainan Medical University Hainan, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue engineering technology provides a promising approach for cartilage repair, and in this strategy, scaffolds play a pivotal role in directing cartilage regeneration. Fish collagen (FC) is currently considered an alternative source of mammalian collagen (MC) for tissue engineering due to its excellent biocompatibility, suitable biodegradability, inert immunogenicity, rich sources, low price and lack of risk for the transmission of zoonosis. Here, we fabricated three types of electrospun nanofibrous membranes composed of FC and polycaprolactone (PCL) with three different FC/PCL ratios (9/1, 7/3, 5/5) and investigated the feasibility of using the membranes with chondrocytes in cartilage regeneration. Our results demonstrated that increases in the FC content were associated with improvements in biodegradability, absorption, and cell adhesion capacity, but weaker mechanical properties. In addition, all three nanofibrous membranes showed satisfactory biocompatibility as evidenced by supporting chondrocyte proliferation and cartilage formation

Indexed as

biomaterialscartilage regenerationelectrospunFish collagentissue engineering

Identifiers

PMID32774732
PMCPMC7407687

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.