Evidence map›Paper›PMID 32774716›Full record

ArticleAmerican journal of translational research2020

Astragaloside IV alleviates puromycin aminonucleoside-induced podocyte cytoskeleton injury through the Wnt/PCP pathway.

Youjia Zeng, Bing Zhang, Xinhui Liu, Liangping He, Taifen Wang, Xuewen Yu, Yuqi Kang, Shunmin Li

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Youjia ZengDepartment of Nephrology, Shenzhen Traditional Chinese Medicine Hospital Shenzhen 518033, Guangdong, China.
Bing ZhangThe Fourth Clinical Medical College, Guangzhou University of Chinese Medicine Shenzhen 518033, China.
Xinhui LiuDepartment of Nephrology, Shenzhen Traditional Chinese Medicine Hospital Shenzhen 518033, Guangdong, China.
Liangping HeDepartment of Nephrology, Traditional Chinese Medicine Hospital of Jiulongpo District in Chongqing Chongqing 400000, China.
Taifen WangDepartment of Nephrology, Shenzhen Traditional Chinese Medicine Hospital Shenzhen 518033, Guangdong, China.
Xuewen YuDepartment of Nephrology, Shenzhen Traditional Chinese Medicine Hospital Shenzhen 518033, Guangdong, China.
Yuqi KangThe Fourth Clinical Medical College, Guangzhou University of Chinese Medicine Shenzhen 518033, China.
Shunmin LiDepartment of Nephrology, Shenzhen Traditional Chinese Medicine Hospital Shenzhen 518033, Guangdong, China.
Shenzhen Pingle Orthopedic Hospital · CNGuangzhou University of Chinese Medicine · CNChongqing Jiulongpo People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Podocyte injury is a common cause of massive proteinuria. Astragaloside IV (AS-IV) has been reported to protect podocytes in diabetic models. However, the effects and potential mechanism of AS-IV on puromycin aminonucleoside (PAN)-induced podocyte injury remains unclear. The aim of the present study was to investigate the protective effect of AS-IV on PAN-induced podocyte injury both

Indexed as

Astragaloside IVcytoskeletonplanar-cell polarity pathwaypodocytepuromycin aminonucleoside

Identifiers

PMID32774716
PMCPMC7407721
OpenAlexW3049361319

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.