Evidence map›Paper›PMID 32774672›Full record

ArticleOxidative medicine and cellular longevity2020

Anti-Diabetic Atherosclerosis by Inhibiting High Glucose-Induced Vascular Smooth Muscle Cell Proliferation via Pin1/BRD4 Pathway.

Yuansheng Wu, Meijin Zhang, Changsheng Xu, Dajun Chai, Feng Peng, Jinxiu Lin

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yuansheng WuThe First Clinical Medical College, Fujian Medical University, Fuzhou, Fujian, China.
Meijin ZhangDepartment of Cardiology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China.
Changsheng XuFujian Provincial Institute of Hypertension, the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China.
Dajun ChaiDepartment of Cardiology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China.
Feng PengDepartment of Cardiology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China.ORCID https://orcid.org/0000-0001-6839-3478
Jinxiu LinDepartment of Cardiology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China.ORCID https://orcid.org/0000-0003-1035-2993
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

methodsDiabetic

resultsJuglone and JQ1 significantly improved atherosclerosis of diabetic

conclusionsInhibition of Pin1/BRD4 pathway may improve diabetic atherosclerosis by inhibiting proliferation and migration of VSMCs.

Indexed as

AnimalsAtherosclerosisBromodomain Containing ProteinsCell ProliferationGlucoseHumansMaleMiceMuscle, Smooth, VascularNuclear ProteinsTranscription FactorsBrd4 protein, mouseBromodomain Containing ProteinsGlucoseNuclear ProteinsTranscription Factors

Identifiers

PMID32774672
PMCPMC7396119
OpenAlexW3045410437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.