Evidence map›Paper›PMID 32774405›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2020

Effects of Tart Cherry Powder on Serum Uric Acid in Hyperuricemia Rat Model.

Ruirui Li, Yuefeng Tan, Yanxia Li, Xia Zhu, Xinyao Tang, Lishi Zhang, Jinyao Chen

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06084585 (A Three Arms, Randomized, Double-blind Controlled Trial of the Efficacy of Amway Uric Acid Lowering Product on Hyperuricemia), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06084585 naunknown statusnot on this mapstarted 2023, after this paper: background citation

A Three Arms, Randomized, Double-blind Controlled Trial of the Efficacy of Amway Uric Acid Lowering Product on Hyperuricemia

TypeinterventionalSponsorAmway (China) R&D CenterRan2023 to 2024Enrolled180ConditionsHyperuricemiaArmsStudy Product A (High-dose 2X), Study Product B (Low-dose X), Placebo
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Plantaginis Semen Ameliorates Hyperuricemia Induced by Potassium Oxonate.International journal of molecular sciences · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ruirui LiWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Yuefeng TanWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Yanxia LiWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Xia ZhuWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Xinyao TangWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Lishi ZhangWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0001-7293-8362
Jinyao ChenWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0003-0519-4935
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperuricemia, as a critical risk factor for various adverse clinical outcomes, shows a trend of increasing prevalence among young-aged population. Dietary adjuvant therapy by function foods, such as tart cherry, is promising. Thus, effects of tart cherry powder specialized in hyperuricemia were explored via establishing a hyperuricemia model in Sprague Dawley rats by cotreatment with oteracil potassium and adenine. The results indicated that low dose of tart cherry powder (0.17 g/kg·bw) showed effects on hyperuricemia by slightly decreasing serum uric acid and improving kidney injury, whereas high dose of tart cherry powder (0.50 g/kg·bw) could merely alleviate kidney injury. Meanwhile, adenosine deaminase activity rather than xanthine oxidase activity was affected at low dose, which reveals low dose of tarty cherry powder may be beneficial to hyperuricemia through reduction of ADA activity, and its reported potentials on antioxidation or anti-inflammation provide clues for further study.

Identifiers

PMID32774405
PMCPMC7396008
OpenAlexW3044761714

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.