Evidence map›Paper›PMID 32774371›Full record

ArticleJournal of oncology2020

The Value of Preoperative Alpha-L-Fucosidase Levels in Evaluation of Malignancy and Differential Diagnosis of Urothelial Neoplasms.

Dongshan Chen, Naidong Xing, Zhanwu Cui, Cong Zhang, Zhao Zhang, Dawei Li, Lei Yan

Open access · hybridAbstract read
In one paragraph

Article in Journal of oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Dongshan Chen *Department of Urology, Qilu Hospital of Shandong University, Wenhuaxi Road 107#, Jinan 250012, China.ORCID https://orcid.org/0000-0003-3479-3144
Naidong Xing *Department of Urology, Qilu Hospital of Shandong University, Wenhuaxi Road 107#, Jinan 250012, China.
Zhanwu CuiDepartment of Urology, Second Traditional Chinese Medicine Hospital of Dezhou City, Zhongxing Road 245#, Dezhou 253500, China.
Cong ZhangDepartment of Urology, Qilu Hospital of Shandong University, Wenhuaxi Road 107#, Jinan 250012, China.
Zhao ZhangDepartment of Urology, Qilu Hospital of Shandong University, Wenhuaxi Road 107#, Jinan 250012, China.ORCID https://orcid.org/0000-0002-3312-4849
Dawei LiDepartment of Urology, Qilu Hospital of Shandong University, Wenhuaxi Road 107#, Jinan 250012, China.
Lei YanDepartment of Urology, Qilu Hospital of Shandong University, Wenhuaxi Road 107#, Jinan 250012, China.ORCID https://orcid.org/0000-0002-4215-6906
Qilu Hospital of Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the role of Alpha-L-fucosidase (AFU) in diagnosis and differential diagnosis of pure urothelial carcinoma (UC), urothelial carcinoma with squamous differentiation (UCSD), and squamous cell carcinoma (SqCC).

methodsA retrospective study was performed for 599 patients who were histologically confirmed with urothelial tumor. Preoperative AFU levels were compared across the distinct subgroups with different clinicopathological parameters. ROC curve analysis and logistic regression analysis were performed to further evaluate the clinical application value of serum AFU levels in diagnosis and differential diagnosis of urothelial tumors.

resultsThere were no statistically significant differences in the AFU levels between different groups with different malignant degrees (UC versus papilloma and papillary urothelial neoplasm of low malignant potential [PUNLMP], high-grade UC versus low-grade UC, invasive versus noninvasive malignant uroepithelial tumor) and different pathological types (UC, UCSD, and SqCC) (all

conclusionsPreoperative AFU levels cannot serve as a reliable predictor for malignant degree and differential diagnosis, including pure UC, UCSD, and SqCC of urothelial tumors.

Identifiers

PMID32774371
PMCPMC7397432
OpenAlexW3044195377

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.