Evidence map›Paper›PMID 32774367›Full record

ArticleInternational journal of endocrinology2020

Clinical Characteristics and Prevalence of Comorbidities according to Metformin Use in Korean Patients with Type 2 Diabetes.

Sang Ouk Chin, In Gyoon Ha, Sang Youl Rhee, Su Jin Jeong, Suk Chon, Sung Hoon Kim, Kyu Jeung Ahn, Sei Hyun Baik, Yongsoo Park, Moon Suk Nam and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Sang Ouk ChinDepartment of Endocrinology and Metabolism, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0001-5914-3653
In Gyoon HaDepartment of Endocrinology and Metabolism, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Sang Youl RheeDepartment of Endocrinology and Metabolism, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0003-0119-5818
Su Jin JeongStatistics Support Department, Kyung Hee University, Medical Center Science Research Institute, Seoul, Republic of Korea.
Suk ChonDepartment of Endocrinology and Metabolism, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Sung Hoon KimDivision of Endocrinology and Metabolism, Department of Medicine, Cheil General Hospital and Women's Healthcare Center, College of Medicine, Dankook University, Yongin, Republic of Korea.
Kyu Jeung AhnDepartment of Endocrinology and Metabolism, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Sei Hyun BaikDivision of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Korea University, Seoul, Republic of Korea.
Yongsoo ParkDepartment of Internal Medicine, College of Medicine, Hanyang University, Seoul, Republic of Korea.
Moon Suk NamDepartment of Internal Medicine, College of Medicine, Inha University, Incheon, Republic of Korea.
Kwan Woo LeeDepartment of Endocrinology and Metabolism, College of Medicine, Ajou University, Suwon, Republic of Korea.ORCID https://orcid.org/0000-0002-7965-9662
Jeong Taek WooDepartment of Endocrinology and Metabolism, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0001-9201-0713
Kyung Hee University · KRAjou University · KRCheil General Hospital and Women's Healthcare Center · KRHanyang University · KRInha University · KRKorea University · KRKyung Hee University Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

methodsThis cross-sectional study based on the Korean National Diabetes Program 2 registry used its baseline clinical data collected from seven participating university hospitals in Korea. Patients with no significant changes in their oral hypoglycemic agents and no diabetes-related complications within the year prior to participation were enrolled. Patients' clinical characteristics according to metformin use were analyzed.

resultsAmong 858 subjects included in the analyses, 706 were metformin users and 152 were nonmetformin users. Metformin users were significantly younger and had higher and glycated hemoglobin with significantly lower rates of accompanying microvascular complications such as retinopathy, cataracts, overt proteinuria, renal insufficiency, and peripheral neuropathy than nonusers. Meanwhile, there was a significantly lower prevalence of malignancy and depression among metformin users. These associations remained significant in multivariate analyses. The prevalence rate of macrovascular complications was not significantly different between the two groups.

conclusionsThere were significant differences with respect to clinical characteristics and comorbidity prevalence according to metformin use among Korean type 2 diabetes patients. Long-term follow-up of these patients is necessary to observe how this difference will affect clinical outcomes for these patients.

Identifiers

PMID32774367
PMCPMC7396103
OpenAlexW3044902086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.