ArticleIndian journal of psychiatry
Nonadherence in bipolar disorder patients: A 14-year retrospective study.
Article in Indian journal of psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Nurse-led treatment engagement interventions for persons with severe mental illnesses in community settings.World journal of psychiatry · 2025Review
- Drug adherence attitude in patients with bipolar disorder and unipolar depression: Insights from a cross-sectional study in central India.Journal of family medicine and primary care · 2025Article
- Research on clinical aspects of bipolar disorder: A review of Indian studies.Indian journal of psychiatry · 2024Review
- Medication nonadherence and its associated factors in psychiatric patients in India: A systematic review and meta-analysis.Indian journal of psychiatry · 2023Review
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3 authors.
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Abstract
backgroundBipolar disorder is a disabling psychiatric disorder. The existing literature suggests about 41% of patients to be nonadherent. Nonadherence leads to relapses, delay in recovery besides higher inpatient care cost as well as higher global cost of the disease. Nonadherence in bipolar affective disorder (BPAD) is a complex phenomenon, its critical determinants are yet to be identified with certainty.
aimsThis study aims to assess the prevalence of nonadherence in BPAD and to delineate the factors associated with it.
methodsMedical records were reviewed in this study from 2005 to 2019 at a medical college in Kerala. Patients who were diagnosed with BPAD according to International Classification of Diseases 10 and who were needing or opting for prophylaxis were included. Patients who were not taking medications for at least 1 week were termed as nonadherent. We included 150 participants in our study.
resultsTo test the statistical significance of the association of categorical variables between H/O of adherence and nonadherence, Chi-square test was used. In the sample, 82.7% had at least 1 week of history of noncompliance in the past. The most common reason was poor understanding of illness by the family (56%) followed by a negative aspect of the patient toward the drug (20%).
conclusionTherefore, this study concludes that though majority of the patients have a history of nonadherence of at least 1 week on long-term follow-up, it was seen that majority of the patients were more than 80% adherent to medications.
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